[HTML][HTML] Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

Research Review: Pediatric anxiety disorders–what have we learnt in the last 10 years?

JR Strawn, L Lu, TS Peris, A Levine… - Journal of Child …, 2021 - Wiley Online Library
Background Anxiety disorders first emerge during the critical developmental periods of
childhood and adolescence. This review synthesizes recent findings on the prevalence, risk …

[PDF][PDF] A comprehensive review of the generalized anxiety disorder

AK Mishra, AR Varma, A Varma - Cureus, 2023 - cureus.com
Excessive, uncontrollable, and usually unjustified worry about certain things is a sign of the
mental and behavioral disease known as generalized anxiety disorder (GAD). Genetic …

Pharmacological treatment of generalised anxiety disorder: current practice and future directions

HA Fagan, DS Baldwin - Expert Review of Neurotherapeutics, 2023 - Taylor & Francis
ABSTRACT Introduction Generalized Anxiety Disorder (GAD) is a common psychiatric
condition, characterized by the presence of general apprehensiveness and excessive worry …

[HTML][HTML] Pulmonary inhalation for disease treatment: Basic research and clinical translations

B Wang, L Wang, Q Yang, Y Zhang, T Qinglai, X Yang… - Materials Today Bio, 2024 - Elsevier
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with
few systemic side effects. In addition, it is non-invasive and has good patient compliance …

[HTML][HTML] Liposome-derived nanosystems for the treatment of behavioral and neurodegenerative diseases: The promise of niosomes, transfersomes, and ethosomes for …

PC Pires, AC Paiva-Santos, F Veiga - Pharmaceuticals, 2023 - mdpi.com
Psychiatric and neurodegenerative disorders are amongst the most prevalent and
debilitating diseases, but current treatments either have low success rates, greatly due to the …

Agomelatine for the treatment of generalized anxiety disorder: focus on its distinctive mechanism of action

MJ Millan - Therapeutic Advances in Psychopharmacology, 2022 - journals.sagepub.com
Generalized anxiety disorder (GAD), the most frequently diagnosed form of anxiety, is
usually treated by cognitive-behavioural approaches or medication; in particular …

Escitalopram in adolescents with generalized anxiety disorder: a double-blind, randomized, placebo-controlled study

JR Strawn, JA Mills, H Schroeder… - The Journal of clinical …, 2020 - psychiatrist.com
Background: Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat
pediatric anxiety disorders, including generalized anxiety disorder (GAD); however, their …

Altered serum interleukin-17A and interleukin-23A levels may be associated with the pathophysiology and development of generalized anxiety disorder

ASM Roknuzzaman, R Sarker, J Nayem… - Scientific Reports, 2024 - nature.com
In recent times, the pathogenesis of generalized anxiety disorder (GAD) and the influence of
pro-and anti-inflammatory cytokines on it have garnered considerable interest. Cytokine …

[HTML][HTML] A review of non-invasive drug delivery through respiratory routes

YB Zhang, D Xu, L Bai, YM Zhou, H Zhang, YL Cui - Pharmaceutics, 2022 - mdpi.com
With rapid and non-invasive characteristics, the respiratory route of administration has
drawn significant attention compared with the limitations of conventional routes. Respiratory …