Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

Dysbiosis of the gut and lung microbiome has a role in asthma

K Hufnagl, I Pali-Schöll, F Roth-Walter… - Seminars in …, 2020 - Springer
Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

The lung microbiome during health and disease

K Yagi, GB Huffnagle, NW Lukacs, N Asai - International Journal of …, 2021 - mdpi.com
Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

Functional effects of the microbiota in chronic respiratory disease

KF Budden, SD Shukla, SF Rehman… - The Lancet …, 2019 - thelancet.com
The composition of the lung microbiome is increasingly well characterised, with changes in
microbial diversity or abundance observed in association with several chronic respiratory …

The role of the lung microbiota and the gut–lung axis in respiratory infectious diseases

A Dumas, L Bernard, Y Poquet… - Cellular …, 2018 - Wiley Online Library
The pulmonary microbial community, described only a few years ago, forms a discreet part
of the human host microbiota. The airway microbiota has been found to be substantially …

Cervicovaginal microbiota and local immune response modulate the risk of spontaneous preterm delivery

MA Elovitz, P Gajer, V Riis, AG Brown… - Nature …, 2019 - nature.com
Failure to predict and understand the causes of preterm birth, the leading cause of neonatal
morbidity and mortality, have limited effective interventions and therapeutics. From a cohort …

Unexpected guests in the tumor microenvironment: microbiome in cancer

A Wong-Rolle, HK Wei, C Zhao, C ** - Protein & cell, 2021 - academic.oup.com
Although intestinal microbiome have been established as an important biomarker and
regulator of cancer development and therapeutic response, less is known about the role of …