COVID-19, renin-angiotensin system and endothelial dysfunction
The newly emergent novel coronavirus disease 2019 (COVID-19) outbreak, which is caused
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
Thrombotic regulation from the endothelial cell perspectives
M Wang, H Hao, NJ Leeper, L Zhu - … , thrombosis, and vascular …, 2018 - Am Heart Assoc
Wang et al Endothelium in Thrombosis e91 endothelial TF may be enhanced in
pathophysiological conditions, 16, 17 and ECs were found to be able to secret …
pathophysiological conditions, 16, 17 and ECs were found to be able to secret …
Insights into immunothrombosis: the interplay among neutrophil extracellular trap, von Willebrand factor, and ADAMTS13
J Yang, Z Wu, Q Long, J Huang, T Hong… - Frontiers in …, 2020 - frontiersin.org
Both neutrophil extracellular traps (NETs) and von Willebrand factor (VWF) are essential for
thrombosis and inflammation. During these processes, a complex series of events, including …
thrombosis and inflammation. During these processes, a complex series of events, including …
An integrin αIIbβ3 intermediate affinity state mediates biomechanical platelet aggregation
Integrins are membrane receptors that mediate cell adhesion and mechanosensing. The
structure–function relationship of integrins remains incompletely understood, despite the …
structure–function relationship of integrins remains incompletely understood, despite the …
Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module
Von Willebrand factor (VWF) activates in response to shear flow to initiate hemostasis, while
aberrant activation could lead to thrombosis. Above a critical shear force, the A1 domain of …
aberrant activation could lead to thrombosis. Above a critical shear force, the A1 domain of …
The power of touch: type 4 pili, the von Willebrand a domain, and surface sensing by Pseudomonas aeruginosa
Most microbes in the biosphere are attached to surfaces, where they experience mechanical
forces due to hydrodynamic flow and cell-to-substratum interactions. These forces likely …
forces due to hydrodynamic flow and cell-to-substratum interactions. These forces likely …
Water‐Assisted Programmable Assembly of Flexible and Self‐Standing Janus Membranes
Q Yi, M Qiu, X Sun, H Wu, Y Huang, H Xu… - Advanced …, 2023 - Wiley Online Library
Janus membranes with asymmetric wettability have been considered cutting‐edge for
energy/environmental‐sustainable applications like water/fog harvester, breathable skin …
energy/environmental‐sustainable applications like water/fog harvester, breathable skin …
Controlling optical and catalytic activity of genetically engineered proteins by ultrasound
Ultrasound (US) produces cavitation‐induced mechanical forces stretching and breaking
polymer chains in solution. This type of polymer mechanochemistry is widely used for …
polymer chains in solution. This type of polymer mechanochemistry is widely used for …
Force-induced changes of PilY1 drive surface sensing by Pseudomonas aeruginosa
During biofilm formation, the opportunistic pathogen Pseudomonas aeruginosa uses its type
IV pili (TFP) to sense a surface, eliciting increased second-messenger production and …
IV pili (TFP) to sense a surface, eliciting increased second-messenger production and …
Nanopores: a versatile tool to study protein dynamics
Proteins are the active workhorses in our body. These biomolecules perform all vital cellular
functions from DNA replication and general biosynthesis to metabolic signaling and …
functions from DNA replication and general biosynthesis to metabolic signaling and …