Microbial rhodopsins: the last two decades

A Rozenberg, K Inoue, H Kandori… - Annual review of …, 2021 - annualreviews.org
Microbial rhodopsins are diverse photoreceptive proteins containing a retinal chromophore
and are found in all domains of cellular life and are even encoded in genomes of viruses …

Rhodopsins at a glance

T Nagata, K Inoue - Journal of Cell Science, 2021 - journals.biologists.com
Rhodopsins are photoreceptive membrane proteins consisting of a common heptahelical
transmembrane architecture that contains a retinal chromophore. Rhodopsin was first …

Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels

A Rozenberg, I Kaczmarczyk, D Matzov… - Nature structural & …, 2022 - nature.com
Many organisms sense light using rhodopsins, photoreceptive proteins containing a retinal
chromophore. Here we report the discovery, structure and biophysical characterization of …

Plastid-localized xanthorhodopsin increases diatom biomass and ecosystem productivity in iron-limited surface oceans

J Strauss, L Deng, S Gao, A Toseland, C Bachy… - Nature …, 2023 - nature.com
Microbial rhodopsins are photoreceptor proteins that convert light into biological signals or
energy. Proteins of the xanthorhodopsin family are common in eukaryotic photosynthetic …

NeoR, a near-infrared absorbing rhodopsin

M Broser, A Spreen, PE Konold, E Schiewer… - Nature …, 2020 - nature.com
The Rhizoclosmatium globosum genome encodes three rhodopsin-guanylyl cyclases
(RGCs), which are predicted to facilitate visual orientation of the fungal zoospores. Here, we …

The red edge: bilin-binding photoreceptors as optogenetic tools and fluorescence reporters

K Tang, HM Beyer, MD Zurbriggen… - Chemical …, 2021 - ACS Publications
This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …

Schizorhodopsins: A family of rhodopsins from Asgard archaea that function as light-driven inward H+ pumps

K Inoue, SP Tsunoda, M Singh, S Tomida… - Science …, 2020 - science.org
Schizorhodopsins (SzRs), a rhodopsin family first identified in Asgard archaea, the archaeal
group closest to eukaryotes, are present at a phylogenetically intermediate position between …

Multiple retinal isomerizations during the early phase of the bestrhodopsin photoreaction

S Kaziannis, M Broser… - Proceedings of the …, 2024 - National Acad Sciences
Bestrhodopsins constitute a class of light-regulated pentameric ion channels that consist of
one or two rhodopsins in tandem fused with bestrophin ion channel domains. Here, we …

Optogenetic manipulation of neuronal and cardiomyocyte functions in zebrafish using microbial rhodopsins and adenylyl cyclases

H Hagio, W Koyama, S Hosaka, AD Song… - Elife, 2023 - elifesciences.org
Even though microbial photosensitive proteins have been used for optogenetics, their use
should be optimized to precisely control cell and tissue functions in vivo. We exploited …

Viral rhodopsins 1 are an unique family of light-gated cation channels

D Zabelskii, A Alekseev, K Kovalev, V Rankovic… - Nature …, 2020 - nature.com
Phytoplankton is the base of the marine food chain as well as oxygen and carbon cycles and
thus plays a global role in climate and ecology. Nucleocytoplasmic Large DNA Viruses that …