[HTML][HTML] Gut microbiota dysbiosis, oxidative stress, inflammation, and epigenetic alterations in metabolic diseases

H Mostafavi Abdolmaleky, JR Zhou - Antioxidants, 2024 - mdpi.com
Gut dysbiosis, resulting from an imbalance in the gut microbiome, can induce excessive
production of reactive oxygen species (ROS), leading to inflammation, DNA damage …

The emerging role of oxidative stress in inflammatory bowel disease

P Muro, L Zhang, S Li, Z Zhao, T **, F Mao… - Frontiers in …, 2024 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic immune-mediated condition that affects the
digestive system and includes Crohn's disease (CD) and ulcerative colitis (UC). Although …

Inflammatory bowel disease: a comprehensive analysis of molecular bases, predictive biomarkers, diagnostic methods, and therapeutic options

E Diez-Martin, L Hernandez-Suarez… - International Journal of …, 2024 - mdpi.com
In inflammatory bowel diseases (IBDs), such as Crohn's disease (CD) and ulcerative colitis
(UC), the immune system relentlessly attacks intestinal cells, causing recurrent tissue …

Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat's colon by augmentation of apoptotic proteins and antioxidant mechanisms

K Abdul-Aziz Ahmed, AAJ Jabbar, MA Abdulla… - Scientific Reports, 2024 - nature.com
Mangiferin (MF) is a natural C-glucosylxantone compound that has many substantial
curative potentials against numerous illnesses including cancers. The present study's goal is …

[HTML][HTML] Redox homeostasis, gut microbiota, and epigenetics in neurodegenerative diseases: A systematic review

C Munteanu, AI Galaction, M Turnea, CD Blendea… - Antioxidants, 2024 - mdpi.com
Neurodegenerative diseases encompass a spectrum of disorders marked by the
progressive degeneration of the structure and function of the nervous system. These …

Boric acid (boron) attenuates AOM-induced colorectal cancer in rats by augmentation of apoptotic and antioxidant mechanisms

AAJ Jabbar, ZZ Alamri, MA Abdulla… - … Trace Element Research, 2024 - Springer
Boric acid (BA) is a naturally occurring weak Lewis acid containing boron, oxygen, and
hydrogen elements that can be found in water, soil, and plants. Because of its numerous …

Microbial assimilatory sulfate reduction-mediated H2S: an overlooked role in Crohn's disease development

W Luo, M Zhao, M Dwidar, Y Gao, L **ang, X Wu… - Microbiome, 2024 - Springer
Background H2S imbalances in the intestinal tract trigger Crohn's disease (CD), a chronic
inflammatory gastrointestinal disorder characterized by microbiota dysbiosis and barrier …

The role of gut microbiota in intestinal disease: From an oxidative stress perspective

Y Sun, X Wang, L Li, C Zhong, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Recent studies have indicated that gut microbiota-mediated oxidative stress is significantly
associated with intestinal diseases such as colorectal cancer, ulcerative colitis, and Crohn's …

[HTML][HTML] Redox homeostasis and molecular biomarkers in precision therapy for cardiovascular diseases

CM Drăgoi, CC Diaconu, AC Nicolae… - …, 2024 - pmc.ncbi.nlm.nih.gov
Precision medicine is envisioned as the future of cardiovascular healthcare, offering a more
tailored and effective method for managing cardiovascular diseases compared to the …

Endoplasmic reticulum stress related genome-wide Mendelian randomization identifies therapeutic genes for ulcerative colitis and Crohn's disease

M Zou, Q Liang, W Zhang, Y Zhu, Y Xu - Frontiers in Genetics, 2023 - frontiersin.org
Background: Endoplasmic reticulum stress (ERS) is an important pathophysiological
mechanism in ulcerative colitis (UC) and Crohn's disease (CD). ERS-related genes may be …