Autophagy is a conserved lysosomal degradation pathway where cellular components are
dynamically degraded and re-processed to maintain physical homeostasis. However, the …

Angiogenesis is a multi-stage process of new blood vessel development from pre-existing
vessels toward an angiogenic stimulus. The process is essential for tissue maintenance and …

Histone modifications (HMs) contribute to maintaining genomic stability, transcription, DNA
repair, and modulating chromatin in cancer cells. Furthermore, HMs are dynamic and …

Metastasis is a complex process that involved in various genetic and epigenetic alterations
during the progression of breast cancer. Recent evidences have indicated that the mutation …

Histone deacetylase 6 (HDAC6) has been shown to be involved in various pathological
conditions, including cancer, neurodegenerative disorders and inflammatory diseases …

To contend with the deleterious effects of accumulating misfolded protein aggregates or
damaged organelles cells rely on a system of quality control processes, among them the …

Although autophagy is a well-known and extensively described cell pathway, numerous
studies have been recently interested in studying the importance of its regulation at different …

Dysregulated epigenetic enzymes and resultant abnormal epigenetic modifications (EMs)
have been suggested to be closely related to tumor occurrence and progression. Histone …

Ketone bodies, including acetoacetate and β-hydroxybutyrate (βOHB), are produced from
acetyl coenzyme A in the liver and then secreted into the blood. These molecules are a …

Long treatment with paclitaxel (PTX) might increase resistance and side-effects causing a
failure in cancer chemotherapy. Here we uncovered that either sulforaphane-cysteine (SFN …