Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Capillary electrophoresis (CE) offers fast and high‐resolution separation of charged
analytes from small injection volumes. Coupled to mass spectrometry (MS), it represents a …

Proteins can undergo glycosylation during and/or after translation to afford glycoconjugates,
which are often secreted by a cell or populate cell surfaces. Changes in the glycan portion …

Capillary electrophoresis has emerged as a powerful approach for carbohydrate analyses
since 2014. The method provides high resolution capable of separating carbohydrates by …

Capillary electrophoresis (CE) has emerged as a powerful technique for comprehensive
physicochemical characterization of monoclonal antibodies (mAbs) as well as other …

Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …

Protein N-and O-glycosylation are well known co-and post-translational modifications of
immunoglobulins. Antibody glycosylation on the Fab and Fc portion is known to influence …

Protein glycosylation is one of the most common post-translational modifications that are
essential for cell function across all domains of life. Changes in glycosylation are considered …

N-glycosylation of therapeutic antibodies starts as a co-translational step followed by a set of
post-translational modifications and is considered as one of the critical quality attributes …

This article illustrates the basis and applications of methodologies for the analysis of simple
and complex carbohydrates by means of CE. After a description of the most common and …