Intrinsically disordered proteins (IDPs) and multidomain proteins with flexible linkers show a
high level of structural heterogeneity and are best described by ensembles consisting of …

The surfactant-macromolecule interactions (SMI) are one of the most critical topics for
scientific research and industrial application. Small-angle X-ray scattering (SAXS) is a …

Drug discovery relies on efficient identification of small-molecule leads and their interactions
with macromolecular targets. However, understanding how chemotypes impact …

Structure-based drug design (SBDD) is a prominent method in rational drug development
and has traditionally benefitted from the atomic models of protein targets obtained using X …

We prove that the transport of any differentiable scalar observable in d-dimensional
nonequilibrium systems is bounded from above by the total entropy production scaled by the …

RNA macromolecules, like proteins, fold to assume shapes that are intimately connected to
their broadly recognized biological functions; however, because of their high charge and …

Infections caused by Staphylococcus aureus depend on its ability to acquire nutrients. One
essential nutrient is iron, which is obtained from the heme of the human host hemoglobin …

The structure of a protein is closely related to its biological function. In this regard, structural
changes, as well as static structures, have been scrutinized as essential elements in …

In-situ characterization techniques, although complex, can provide a wealth of insight into
material chemistry and evolution dynamics. Gras** the fundamental kinetics of material …

The cardiac sarcomere is a cellular structure in the heart that enables muscle cells to
contract. Dozens of proteins belong to the cardiac sarcomere, which work in tandem to …