PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

Advances and potential application of gold nanoparticles in nanomedicine

TS Lopes, GG Alves, MR Pereira… - Journal of cellular …, 2019 - Wiley Online Library
Nanomedicine is an emerging research area which has brought new possibilities and
promising applications in image, diagnosis, and treatment. Nanoparticles (NPs) for …

Shear stress and ROS-responsive biomimetic micelles for atherosclerosis via ROS consumption

M Shen, H Li, S Yao, X Wu, S Liu, Q Yang… - Materials Science and …, 2021 - Elsevier
Reactive oxygen species (ROS) are well-known important initiating factors required for
atherosclerosis formation, which leads to endothelial dysfunction and plaque formation …

Repurposing drug molecules for new pulmonary therapeutic interventions

PP Mehta, VS Dhapte-Pawar - Drug Delivery and Translational Research, 2021 - Springer
Drug repurposing with novel strategies has substantially contributed to the identification and
analysis of new molecules for better pulmonary intervention. This review would offer insights …

Nano methotrexate versus methotrexate in targeting rheumatoid arthritis

HF Salem, MM Abd El-Maboud, ASA Said, MN Salem… - Pharmaceuticals, 2022 - mdpi.com
Nanomedicine has emerged as an important approach for targeting RA medication.
Rheumatoid arthritis (RA) is a widespread autoimmune disorder marked by multiple …

Emerging therapies for smoke inhalation injury: a review

A Mercel, ND Tsihlis, R Maile, MR Kibbe - Journal of translational …, 2020 - Springer
Background Smoke inhalation injury increases overall burn mortality by up to 20 times.
Current therapy remains supportive with a failure to identify an optimal or targeted treatment …

A dose‐related positive effect of inhaled simvastatin‐loaded PLGA nanoparticles on paraquat‐induced pulmonary fibrosis in rats

N Shahabadi, M Moshiri, A Roohbakhsh… - Basic & Clinical …, 2022 - Wiley Online Library
Objective Pulmonary fibrosis is an important complication of subacute paraquat (PQ)
poisoning. Here, we reported a novel nanotherapeutic platform for PQ‐induced pulmonary …

[HTML][HTML] In vitro bio-characterization of solid lipid nanoparticles of favipiravir in A549 human lung epithelial cancer cells

AS Tulbah - Journal of Taibah University Medical Sciences, 2023 - Elsevier
Lung cancer is a leading cause of mortality worldwide. 1, 2 Recently, its incidence has
increased because of smoking and environmental pollution. 3 Surgery, radiation therapy …

Physicochemical characteristics and in vitro toxicity/anti-SARS-CoV-2 activity of favipiravir solid lipid nanoparticles (SLNs)

AS Tulbah, WH Lee - Pharmaceuticals, 2021 - mdpi.com
The rise of coronavirus (COVID-19) cases worldwide has driven the need to discover and
develop novel therapeutics with superior efficacy to treat this disease. This study aims to …

Repurposing of statins via inhalation to treat lung inflammatory conditions

P Bradbury, D Traini, AJ Ammit, PM Young… - Advanced Drug Delivery …, 2018 - Elsevier
Despite many therapeutic advancements over the past decade, the continued rise in chronic
inflammatory lung diseases incidence has driven the need to identify and develop new …