Mucosal healing in inflammatory bowel diseases: a systematic review

MF Neurath, SPL Travis - Gut, 2012 - gut.bmj.com
Recent studies have identified mucosal healing on endoscopy as a key prognostic
parameter in the management of inflammatory bowel diseases (IBD), thus highlighting the …

Systematic review: histological remission in inflammatory bowel disease. Is 'complete'remission the new treatment paradigm? An IOIBD initiative

RV Bryant, S Winer, T SPL… - Journal of Crohn's and …, 2014 - academic.oup.com
Background and aims: Advances in the medical management of inflammatory bowel
disease (IBD) have altered treatment targets. Endoscopic mucosal healing is associated …

The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response

X Zong, X **ao, B Shen, Q Jiang, H Wang… - Nucleic acids …, 2021 - academic.oup.com
The intestinal invasion of pathogenic microorganisms can have serious health
consequences. Recent evidence has shown that the N 6-methyladenosine (m6A) mRNA …

Long-term culture captures injury-repair cycles of colonic stem cells

Y Wang, IL Chiang, TE Ohara, S Fujii, J Cheng… - Cell, 2019 - cell.com
The colonic epithelium can undergo multiple rounds of damage and repair, often in
response to excessive inflammation. The responsive stem cell that mediates this process is …

Mitochondrial dysfunction in inflammatory bowel disease

EA Novak, KP Mollen - Frontiers in cell and developmental biology, 2015 - frontiersin.org
Inflammatory Bowel Disease (IBD) represents a group of idiopathic disorders characterized
by chronic or recurring inflammation of the gastrointestinal tract. While the exact etiology of …

Nanoparticulate drug delivery systems targeting inflammation for treatment of inflammatory bowel disease

S Zhang, R Langer, G Traverso - Nano Today, 2017 - Elsevier
Inflammatory bowel disease (IBD) is a chronic, idiopathic inflammatory set of conditions that
can affect the entire gastrointestinal (GI) tract and is associated with an increased risk of …

The impact of weaning stress on gut health and the mechanistic aspects of several feed additives contributing to improved gut health function in weanling piglets—A …

SD Upadhaya, IH Kim - Animals, 2021 - mdpi.com
Simple Summary The current review aimed to provide an overview on the problems
associated with weaning with a special focus on gut health, and also highlighted the …

Microbiota-derived butyrate regulates intestinal inflammation: Focus on inflammatory bowel disease

MR Couto, P Gonçalves, F Magro, F Martel - Pharmacological Research, 2020 - Elsevier
Inflammatory bowel disease (IBD) refers to a group of heterogeneous disorders associated
with chronic inflammation of the gut, having a high rate of incidence in the world. In the …

Mitochondrial function controls intestinal epithelial stemness and proliferation

E Berger, E Rath, D Yuan, N Waldschmitt… - Nature …, 2016 - nature.com
Control of intestinal epithelial stemness is crucial for tissue homeostasis. Disturbances in
epithelial function are implicated in inflammatory and neoplastic diseases of the …

[HTML][HTML] The activation of Wnt signaling by a STAT6-dependent macrophage phenotype promotes mucosal repair in murine IBD

J Cosín-Roger, D Ortiz-Masia, S Calatayud… - Mucosal …, 2016 - Elsevier
The complete repair of the mucosa constitutes a key goal in inflammatory bowel disease
(IBD) treatment. The Wnt signaling pathway mediates mucosal repair and M2 macrophages …