Photodynamic and photothermal therapies: synergy opportunities for nanomedicine

M Overchuk, RA Weersink, BC Wilson, G Zheng - ACS nano, 2023 - ACS Publications
Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …

Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation

S Gimondi, H Ferreira, RL Reis, NM Neves - ACS nano, 2023 - ACS Publications
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …

Lipid nanoparticles for mRNA delivery

X Hou, T Zaks, R Langer, Y Dong - Nature Reviews Materials, 2021 - nature.com
Messenger RNA (mRNA) has emerged as a new category of therapeutic agent to prevent
and treat various diseases. To function in vivo, mRNA requires safe, effective and stable …

Lipids and lipid derivatives for RNA delivery

Y Zhang, C Sun, C Wang, KE Jankovic… - Chemical reviews, 2021 - ACS Publications
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery

L Shi, J Zhang, M Zhao, S Tang, X Cheng, W Zhang… - Nanoscale, 2021 - pubs.rsc.org
The rapid development of drug nanocarriers has benefited from the surface hydrophilic
polymers of particles, which has improved the pharmacokinetics of the drugs. Polyethylene …

An outlook on microfluidics: the promise and the challenge

S Battat, DA Weitz, GM Whitesides - Lab on a Chip, 2022 - pubs.rsc.org
This perspective considers ways in which the field of microfluidics can increase its impact by
improving existing technologies and enabling new functionalities. We highlight applications …

Organic optoelectronic materials: A rising star of bioimaging and phototherapy

KW Lee, Y Wan, Z Huang, Q Zhao, S Li… - Advanced …, 2024 - Wiley Online Library
Recently, many organic optoelectronic materials (OOMs), especially those used in organic
light‐emitting diodes (OLEDs), organic solar cells (OSCs), and organic field‐effect …

Nucleic acid delivery for therapeutic applications

A Gupta, JL Andresen, RS Manan, R Langer - Advanced drug delivery …, 2021 - Elsevier
Recent medical advances have exploited the ability to address a given disease at the
underlying level of transcription and translation. These treatment paradigms utilize nucleic …

Microfluidic nanoparticles for drug delivery

Y Liu, G Yang, Y Hui, S Ranaweera, CX Zhao - Small, 2022 - Wiley Online Library
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …

Microfluidic formulation of nanoparticles for biomedical applications

SJ Shepherd, D Issadore, MJ Mitchell - Biomaterials, 2021 - Elsevier
Nanomedicine has made significant advances in clinical applications since the late-20th
century, in part due to its distinct advantages in biocompatibility, potency, and novel …