2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …
Heart disease and stroke statistics—2023 update: a report from the American Heart Association
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications
As recreational use of cannabis is being decriminalized in many places and medical use
widely sanctioned, there are growing concerns about increases in cannabis use disorder …
widely sanctioned, there are growing concerns about increases in cannabis use disorder …
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders
Genetic liability to substance use disorders can be parsed into loci that confer general or
substance-specific addiction risk. We report a multivariate genome-wide association meta …
substance-specific addiction risk. We report a multivariate genome-wide association meta …
Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …
from complex interplay between genetic and environmental factors. It is well-established that …
Genetics of substance use disorders: a review
Substance use disorders (SUDs) are prevalent and result in an array of negative
consequences. They are influenced by genetic factors (h2=~ 50%). Recent years have …
consequences. They are influenced by genetic factors (h2=~ 50%). Recent years have …
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Most transcriptome-wide association studies (TWASs) so far focus on European ancestry
and lack diversity. To overcome this limitation, we aggregated genome-wide association …
and lack diversity. To overcome this limitation, we aggregated genome-wide association …
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes
Tobacco use disorder (TUD) is the most prevalent substance use disorder in the world.
Genetic factors influence smoking behaviours and although strides have been made using …
Genetic factors influence smoking behaviours and although strides have been made using …
Genetics of substance use disorders in the era of big data
Substance use disorders (SUDs) are conditions in which the use of legal or illegal
substances, such as nicotine, alcohol or opioids, results in clinical and functional …
substances, such as nicotine, alcohol or opioids, results in clinical and functional …
Characterizing the shared genetic underpinnings of schizophrenia and cardiovascular disease risk factors
Objective: Schizophrenia is associated with increased risk of cardiovascular disease (CVD),
although there is variation in risk among individuals. There are indications of shared genetic …
although there is variation in risk among individuals. There are indications of shared genetic …