Significance: Measurement and imaging of hemoglobin oxygenation are used extensively in
the detection and diagnosis of disease; however, the applied instruments vary widely in their …

This report is the second part of a comprehensive two-part series aimed at reviewing an
extensive and diverse toolkit of novel methods to explore brain health and function. While …

Objective. Blood flow is one such available observable promoting a wealth of physiological
insight both individually and in combination with other metrics. Approach. Near-infrared …

Diffuse correlation spectroscopy (DCS) has emerged as a versatile, noninvasive method for
deep tissue perfusion assessment using near-infrared light. A broad class of applications is …

We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement
of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal …

Cerebral blood flow (CBF) is crucial for brain health. Speckle contrast optical spectroscopy
(SCOS) is a technique that has been recently developed to measure CBF, but the use of …

Diffuse correlation spectroscopy (DCS) is an optical technique that can be used to
characterize blood flow in tissue. The measurement of cerebral hemodynamics has arisen …

Significance: The ability of diffuse correlation spectroscopy (DCS) to measure cerebral blood
flow (CBF) in humans is hindered by the low signal-to-noise ratio (SNR) of the method. This …

There is a growing interest in monitoring muscle oxygen saturation (SmO2), which is a
localized measure of muscle oxidative metabolism and can be acquired continuously and …

Commercially available wearable devices have been used for fitness and health
management and their demand has increased over the last ten years. These “general …