A comprehensive review of the PTEN/PI3K/Akt axis in multiple myeloma: from molecular interactions to potential therapeutic targets

M Alimohammadi, P Rahimzadeh, R Khorrami… - … -Research and Practice, 2024 - Elsevier
Phosphatase and tensin homolog (PTEN), phosphatidylinositol 3-kinase (PI3K), and protein
kinase B (Akt) signaling pathways contribute to the development of several cancers …

Detection of early relapse in multiple myeloma patients

T Růžičková, M Vlachová, L Pečinka, M Brychtová… - Cell Division, 2025 - Springer
Background Multiple myeloma (MM) represents the second most common hematological
malignancy characterized by the infiltration of the bone marrow by plasma cells that produce …

MicroRNA Profiling of Bone Marrow Plasma Extracellular Vesicles in Multiple Myeloma, Extramedullary Disease, and Plasma Cell Leukemia

J Gregorova, M Vlachova… - Hematological …, 2025 - Wiley Online Library
Multiple myeloma is a plasma cell malignancy characterized by an abnormal increase in
monoclonal immunoglobulins. Despite significant advances in treatment, some patients …