The naked mole-rat as a model for healthy aging
Naked mole-rats (NMRs, Heterocephalus glaber) are the longest-lived rodents with a
maximum life span exceeding 37 years. They exhibit a delayed aging phenotype and …
maximum life span exceeding 37 years. They exhibit a delayed aging phenotype and …
Carcinogenesis resistance in the longest‐lived rodent, the naked mole‐rat
Certain mammalian species are resistant to cancer, and a better understanding of how this
cancer resistance arises could provide valuable insights for basic cancer research. Recent …
cancer resistance arises could provide valuable insights for basic cancer research. Recent …
Adult stem cell activity in naked mole rats for long-term tissue maintenance
The naked mole rat (NMR), Heterocephalus glaber, the longest-living rodent, provides a
unique opportunity to explore how evolution has shaped adult stem cell (ASC) activity and …
unique opportunity to explore how evolution has shaped adult stem cell (ASC) activity and …
Invariant γδTCR natural killer-like effector T cells in the naked mole-rat
The naked mole-rat (Heterocephalus glaber) is a long-lived rodent species showing
resistance to the development of cancer. Although naked mole-rats have been reported to …
resistance to the development of cancer. Although naked mole-rats have been reported to …
Macrophages from naked mole-rat possess distinct immunometabolic signatures upon polarization
EA Gorshkova, EO Gubernatorova… - Frontiers in …, 2023 - frontiersin.org
The naked mole-rat (NMR) is a unique long-lived rodent which is highly resistant to age-
associated disorders and cancer. The immune system of NMR possesses a distinct cellular …
associated disorders and cancer. The immune system of NMR possesses a distinct cellular …
The infection-tolerant white-footed deermouse tempers interferon responses to endotoxin in comparison to the mouse and rat
A Milovic, JV Duong, AG Barbour - Elife, 2024 - elifesciences.org
The white-footed deermouse Peromyscus leucopus, a long-lived rodent, is a key reservoir in
North America for agents of several zoonoses, including Lyme disease, babesiosis …
North America for agents of several zoonoses, including Lyme disease, babesiosis …
[HTML][HTML] The white-footed deermouse, an infection-tolerant reservoir for several zoonotic agents, tempers interferon responses to endotoxin in comparison to the …
A Milovic, JV Duong, AG Barbour - bioRxiv, 2023 - ncbi.nlm.nih.gov
The white-footed deermouse Peromyscus leucopus, a long-lived rodent, is a key reservoir
for agents of several zoonoses, including Lyme disease. While persistently infected, this …
for agents of several zoonoses, including Lyme disease. While persistently infected, this …
Living a longer life: unique lessons from the naked mole‐rat blood system
R Andersson, MC Florian - The EMBO Journal, 2022 - embopress.org
Analysis of functional deterioration of the blood system during ageing has been largely
confined to the mouse and human system. In this issue, Emmrich et al (2022) report the first …
confined to the mouse and human system. In this issue, Emmrich et al (2022) report the first …
Rejuvenating aged stem cells: therapeutic strategies to extend health and lifespan
F Matteini, S Montserrat‐Vazquez, MC Florian - FEBS letters, 2024 - Wiley Online Library
Aging is associated with a global decline in stem cell function. To date, several strategies
have been proposed to rejuvenate aged stem cells: most of these result in functional …
have been proposed to rejuvenate aged stem cells: most of these result in functional …
Deciphering the aging process through single‐cell cytometric technologies
The advent of single‐cell cytometric technologies, in conjunction with advances in single‐
cell biology, has significantly propelled forward the field of geroscience, enhancing our …
cell biology, has significantly propelled forward the field of geroscience, enhancing our …