The latest in animal models of pulmonary hypertension and right ventricular failure
Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …
Metformin, macrophage dysfunction and atherosclerosis
Metformin is one of the most widely prescribed hypoglycemic drugs and has the potential to
treat many diseases. More and more evidence shows that metformin can regulate the …
treat many diseases. More and more evidence shows that metformin can regulate the …
Pulmonary Hypertension in HFpEF and HFrEF: JACC Review Topic of the Week
M Guazzi, S Ghio, Y Adir - Journal of the American College of Cardiology, 2020 - jacc.org
Pulmonary hypertension (PH) associated with left heart disease, or Group 2 PH, includes
heart failure, valvular heart diseases, and congenital heart diseases. Although it is axiomatic …
heart failure, valvular heart diseases, and congenital heart diseases. Although it is axiomatic …
Pulmonary hypertension: Linking inflammation and pulmonary arterial stiffening
SF Liu, N Nambiar Veetil, Q Li… - Frontiers in …, 2022 - frontiersin.org
Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies
and ultimately leads to right heart failure as the predominant cause of morbidity and …
and ultimately leads to right heart failure as the predominant cause of morbidity and …
Myeloid cell derived IL1β contributes to pulmonary hypertension in HFpEF
BACKGROUND: Pulmonary hypertension (PH) in heart failure with preserved ejection
fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH …
fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH …
Animal models of pulmonary hypertension: Getting to the heart of the problem
JP Dignam, TE Scott, BK Kemp‐Harper… - British Journal of …, 2022 - Wiley Online Library
Despite recent therapeutic advances, pulmonary hypertension (PH) remains a fatal disease
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …
Role of macrophages in pulmonary arterial hypertension
MQ Zhang, CC Wang, XB Pang, JZ Shi, HR Li… - Frontiers in …, 2023 - frontiersin.org
Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary vascular disease
characterized by progressive pulmonary artery pressure elevation, increased pulmonary …
characterized by progressive pulmonary artery pressure elevation, increased pulmonary …
A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the …
Pulmonary hypertension (PH) associated with left heart failure (LHF)(PH‐LHF) is one of the
most common causes of PH. It directly contributes to symptoms and reduced functional …
most common causes of PH. It directly contributes to symptoms and reduced functional …
Understanding the pathobiology of pulmonary hypertension due to left heart disease
JH Huston, SJ Shah - Circulation research, 2022 - Am Heart Assoc
The development of pulmonary hypertension (PH) is common and has adverse prognostic
implications in patients with heart failure due to left heart disease (LHD), and thus far, there …
implications in patients with heart failure due to left heart disease (LHD), and thus far, there …
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life
Obesity is a pre-disposing condition for chronic obstructive pulmonary disease, asthma, and
pulmonary arterial hypertension. Accumulating evidence suggests that metabolic influences …
pulmonary arterial hypertension. Accumulating evidence suggests that metabolic influences …