Decoding type I and III interferon signalling during viral infection

EV Mesev, RA LeDesma, A Ploss - Nature microbiology, 2019 - nature.com
Interferon (IFN)-mediated antiviral responses are central to host defence against viral
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …

Hantavirus pulmonary syndrome

A MacNeil, ST Nichol, CF Spiropoulou - Virus research, 2011 - Elsevier
Hantavirus pulmonary syndrome (HPS) is a severe disease characterized by a rapid onset
of pulmonary edema followed by respiratory failure and cardiogenic shock. The HPS …

The long noncoding RNA NEAT1 exerts antihantaviral effects by acting as positive feedback for RIG-I signaling

H Ma, P Han, W Ye, H Chen, X Zheng, L Cheng… - Journal of …, 2017 - Am Soc Microbiol
Hantavirus infection, which causes zoonotic diseases with a high mortality rate in humans,
has long been a global public health concern. Over the past decades, accumulating …

Molecular insights into Crimean-Congo hemorrhagic fever virus

M Zivcec, FEM Scholte, CF Spiropoulou, JR Spengler… - Viruses, 2016 - mdpi.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen that causes high
morbidity and mortality. Efficacy of vaccines and antivirals to treat human CCHFV infections …

Common themes in zoonotic spillover and disease emergence: Lessons learned from bat-and rodent-borne RNA viruses

EP Williams, BM Spruill-Harrell, MK Taylor, J Lee… - Viruses, 2021 - mdpi.com
Rodents (order Rodentia), followed by bats (order Chiroptera), comprise the largest
percentage of living mammals on earth. Thus, it is not surprising that these two orders …

Hantavirus reservoirs: current status with an emphasis on data from Brazil

R Carvalho de Oliveira, A Guterres, J Fernandes… - Viruses, 2014 - mdpi.com
Since the recognition of hantavirus as the agent responsible for haemorrhagic fever in
Eurasia in the 1970s and, 20 years later, the descovery of hantavirus pulmonary syndrome …

Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential

L Flórez-Álvarez, EE de Souza, VF Botosso… - Frontiers in …, 2022 - frontiersin.org
Hemorrhagic fever viruses (HFVs) pose a threat to global public health owing to the
emergence and re-emergence of highly fatal diseases. Viral hemorrhagic fevers (VHFs) …

The glycoprotein and nucleocapsid protein of hantaviruses manipulate autophagy flux to restrain host innate immune responses

K Wang, H Ma, H Liu, W Ye, Z Li, L Cheng, L Zhang… - Cell reports, 2019 - cell.com
Hantavirus infection, which causes severe zoonotic diseases with high mortality in humans,
has become a global public health concern. Here, we demonstrate that Hantaan virus …

Characterization of biomarker levels in crimean–Congo hemorrhagic fever and hantavirus fever with renal syndrome

M Korva, K Resman Rus, M Pavletič, A Saksida… - Viruses, 2019 - mdpi.com
Hemorrhagic fever with renal syndrome (HFRS) and Crimean-Congo hemorrhagic fever
(CCHF) are important viral hemorrhagic fevers (VHF), especially in the Balkan region …

Biodefense implications of new-world hantaviruses

MH D'Souza, TR Patel - Frontiers in bioengineering and …, 2020 - frontiersin.org
Hantaviruses, part of the Bunyaviridae family, are a genus of negative-sense, single-
stranded RNA viruses that cause two major diseases: New-World Hantavirus …