Foods high in carbohydrates are an important part of a healthy diet, since they provide the
body with glucose to support bodily functions and physical activity. However, the abusive …

The progressive increase in lifespan over the past century carries with it some adversity
related to the accompanying burden of debilitating diseases prevalent in the older …

The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

Metabolism generates oxygen radicals, which contribute to oncogenic mutations. Activated
oncogenes and loss of tumor suppressors in turn alter metabolism and induce aerobic …

Obesity, a growing health problem worldwide, has been associated with the metabolic
syndrome, diabetes, cardiovascular disease, hypertension, and other chronic diseases …

Emerging evidence indicates that impaired cellular energy metabolism is the defining
characteristic of nearly all cancers regardless of cellular or tissue origin. In contrast to normal …

Calorie restriction (CR) extends lifespan and has been shown to reduce age-related
diseases including cancer, diabetes, and cardiovascular and neurodegenerative diseases …

The increasing rate of obesity worldwide is predicted to be associated with a surge in
diseases. Notably, obesity has been linked to approximately 20% of cancer cases in the …

One of the many debated topics in ageing research is whether progeroid syndromes are
really accelerated forms of human ageing. The answer requires a better understanding of …

Healthy individuals can harbour microscopic tumours and dysplastic foci in different organs
in an undetectable and asymptomatic state for many years. These lesions do not progress in …