Impact of hypertension on cognitive function: a scientific statement from the American Heart Association
Background—Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
Vascular contributions to dementia and Alzheimer's disease are increasingly recognized,,,,–.
Recent studies have suggested that breakdown of the blood–brain barrier (BBB) is an early …
Recent studies have suggested that breakdown of the blood–brain barrier (BBB) is an early …
Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
Vascular contributions to cognitive impairment are increasingly recognized,,,–as shown by
neuropathological,, neuroimaging,,,–, and cerebrospinal fluid biomarker, studies. Moreover …
neuropathological,, neuroimaging,,,–, and cerebrospinal fluid biomarker, studies. Moreover …
The science of vascular contributions to cognitive impairment and dementia (VCID): a framework for advancing research priorities in the cerebrovascular biology of …
RA Corriveau, F Bosetti, M Emr, JT Gladman… - Cellular and molecular …, 2016 - Springer
Abstract The World Health Organization reports that 47.5 million people are affected by
dementia worldwide. With aging populations and 7.7 million new cases each year, the …
dementia worldwide. With aging populations and 7.7 million new cases each year, the …
Vascular dysfunction—the disregarded partner of Alzheimer's disease
Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …
Association of data-driven white matter hyperintensity spatial signatures with distinct cerebral small vessel disease etiologies
CL Phuah, Y Chen, JF Strain, N Yechoor… - Neurology, 2022 - AAN Enterprises
Background and Objectives Topographical distribution of white matter hyperintensities
(WMH) are hypothesized to vary by cerebrovascular risk factors. We used an unbiased …
(WMH) are hypothesized to vary by cerebrovascular risk factors. We used an unbiased …
Emerging risk of environmental factors: insight mechanisms of Alzheimer's diseases
Neurodegenerative disorders are typically sporadic in nature in addition to usually
influenced through an extensive range of environmental factors, lifestyle, and genetic …
influenced through an extensive range of environmental factors, lifestyle, and genetic …
Extra-virgin olive oil for potential prevention of Alzheimer disease
GC Román, RE Jackson, J Reis, AN Román… - Revue …, 2019 - Elsevier
Observational epidemiological studies provide valuable information regarding naturally
occurring protective factors observed in populations with very low prevalences of vascular …
occurring protective factors observed in populations with very low prevalences of vascular …
Cerebrovascular damage mediates relations between aortic stiffness and memory
LL Cooper, T Woodard, S Sigurdsson… - …, 2016 - Am Heart Assoc
Aortic stiffness is associated with cognitive decline. Here, we examined the association
between carotid-femoral pulse wave velocity and cognitive function and investigated …
between carotid-femoral pulse wave velocity and cognitive function and investigated …
Cerebral hypoxia: its role in age-related chronic and acute cognitive dysfunction
Postoperative cognitive dysfunction (POCD) has been reported with widely varying
frequency but appears to be strongly associated with aging. Outside of the surgical arena …
frequency but appears to be strongly associated with aging. Outside of the surgical arena …