Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines
After over a billion of vaccinations with messenger RNA-lipid nanoparticle (mRNA-LNP)
based SARS-CoV-2 vaccines, anaphylaxis and other manifestations of hypersensitivity can …
based SARS-CoV-2 vaccines, anaphylaxis and other manifestations of hypersensitivity can …
COVID-19 vaccination in pregnancy, paediatrics, immunocompromised patients, and persons with history of allergy or prior SARS-CoV-2 infection: overview of current …
To date, four vaccines have been authorised for emergency use and under conditional
approval by the European Medicines Agency to prevent COVID-19: Comirnaty, COVID-19 …
approval by the European Medicines Agency to prevent COVID-19: Comirnaty, COVID-19 …
Side effects of mRNA-based COVID-19 vaccine: nationwide phase IV study among healthcare workers in Slovakia
A Riad, B Hocková, L Kantorová, R Slávik, L Spurná… - Pharmaceuticals, 2021 - mdpi.com
mRNA-based COVID-19 vaccines such as BNT162b2 have recently been a target of anti-
vaccination campaigns due to their novelty in the healthcare industry; nevertheless, these …
vaccination campaigns due to their novelty in the healthcare industry; nevertheless, these …
Experience with polyethylene glycol allergy‐guided risk management for COVID‐19 vaccine anaphylaxis
K Brockow, S Mathes, J Fischer, S Volc, U Darsow… - Allergy, 2022 - Wiley Online Library
Background Polyethylene glycol (PEG) may elicit anaphylaxis to COVID‐19 mRNA
vaccines, and guidance for patients at risk is needed. Methods In retrospective patients with …
vaccines, and guidance for patients at risk is needed. Methods In retrospective patients with …
Safety of an inactivated, whole-virion COVID-19 vaccine (CoronaVac) in people aged 60 years or older in Hong Kong: a modified self-controlled case series
Background Because evidence on the safety of COVID-19 vaccines in older adults is scarce,
we aimed to evaluate the incidence and risk of adverse events after CoronaVac (Sinovac …
we aimed to evaluate the incidence and risk of adverse events after CoronaVac (Sinovac …
Adverse events following vaccines: From detection to research translation
E Fernandez, J Jaggers, AE Norton… - Annual Review of …, 2024 - annualreviews.org
Vaccines are lifesaving interventions that reduce the morbidity and mortality of disease.
Fortunately, serious adverse events with vaccination are uncommon, but they must promptly …
Fortunately, serious adverse events with vaccination are uncommon, but they must promptly …
Anaphylaxis to Pfizer/BioNTech mRNA COVID-19 vaccine in a patient with clinically confirmed PEG allergy
Although allergic responses to the mRNA COVID-19 vaccines are rare, recent reports have
suggested that a small number of individuals with allergy to polyethylene glycol (PEG), a …
suggested that a small number of individuals with allergy to polyethylene glycol (PEG), a …
Risk of second allergic reaction to SARS-CoV-2 vaccines: a systematic review and meta-analysis
DK Chu, EM Abrams, DBK Golden… - JAMA internal …, 2022 - jamanetwork.com
Importance Vaccination against SARS-CoV-2 is a highly effective strategy to prevent
infection and severe COVID-19 outcomes. The best strategy for a second dose of vaccine …
infection and severe COVID-19 outcomes. The best strategy for a second dose of vaccine …
A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement …
L Dézsi, T Mészáros, G Kozma, M H-Velkei, CZ Oláh… - Geroscience, 2022 - Springer
A tiny fraction of people immunized with lipid nanoparticle (LNP)-enclosed mRNA (LNP-
mRNA) vaccines develop allergic symptoms following their first or subsequent vaccinations …
mRNA) vaccines develop allergic symptoms following their first or subsequent vaccinations …
[HTML][HTML] Evaluation of association of anti-PEG antibodies with anaphylaxis after mRNA COVID-19 vaccination
ZH Zhou, MM Cortese, JL Fang, R Wood, DS Hummell… - Vaccine, 2023 - Elsevier
Background The mechanism for anaphylaxis following mRNA COVID-19 vaccination has
been widely debated; understanding this serious adverse event is important for future …
been widely debated; understanding this serious adverse event is important for future …