The past decade has seen several critical advances in our understanding of hypothalamic–
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …

Glucocorticoid action on target tissues is determined by the density of “nuclear” receptors
and intracellular metabolism by the two isozymes of 11β-hydroxysteroid dehydrogenase …

Brain Corticosteroid Receptor Balance in Health and Disease* | Endocrine Reviews | Oxford
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

The primary adrenal cortical steroid hormones, aldosterone, and the glucocorticoids cortisol
and corticosterone, act through the structurally similar mineralocorticoid (MR) and …

Daily dietary potassium (K+) intake may be as large as the extracellular K+ pool. To avoid
acute hyperkalemia, rapid removal of K+ from the extracellular space is essential. This is …

This textbook is intended for students and practitioners of herbal medicine, but will also be of
value to other health care professionals. It provides a detailed, practical and research-based …

11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) interconverts inactive cortisone and
active cortisol. Although bidirectional, in vivo it is believed to function as a reductase …

Insulin resistance has been proposed as a mediator of the association between risk factors
for cardiovascular disease in the population. The clinical syndrome of glucocorticoid excess …

Cortisol in obesity is a much-studied problem. Previous information indicates that cortisol
secretion is elevated but that circulatory concentrations are normal or low, suggesting that …

Recent years have seen significant advances in our understanding of the development and
function of the adrenal gland together with further insights into the physiologic and …