Tertiary lymphoid structures and B cells: An intratumoral immunity cycle

WH Fridman, M Meylan, G Pupier, A Calvez… - Immunity, 2023 - cell.com
The generation of anti-tumor immunity in the draining lymph nodes is known as the cancer
immunity cycle. Accumulating evidence supports the occurrence of such a cycle at tumor …

B cells in the tumor microenvironment: Multi-faceted organizers, regulators, and effectors of anti-tumor immunity

CM Laumont, BH Nelson - Cancer Cell, 2023 - cell.com
Our understanding of tumor-infiltrating lymphocytes (TILs) is rapidly expanding beyond T cell-
centric perspectives to include B cells and plasma cells, collectively referred to as TIL-Bs. In …

[HTML][HTML] Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypes

Y Yang, X Chen, J Pan, H Ning, Y Zhang, Y Bo, X Ren… - Cell, 2024 - cell.com
Characterizing the compositional and phenotypic characteristics of tumor-infiltrating B cells
(TIBs) is important for advancing our understanding of their role in cancer development …

[HTML][HTML] An immune cell map of human lung adenocarcinoma development reveals an anti-tumoral role of the Tfh-dependent tertiary lymphoid structure

W Liu, W You, Z Lan, Y Ren, S Gao, S Li, WW Chen… - Cell Reports …, 2024 - cell.com
The immune responses during the initiation and invasion stages of human lung
adenocarcinoma (LUAD) development are largely unknown. Here, we generated a single …

A pan-cancer single-cell RNA-seq atlas of intratumoral B cells

E Fitzsimons, D Qian, A Enica, K Thakkar, M Augustine… - Cancer Cell, 2024 - cell.com
Tumor-infiltrating B cells play a significant role in tumor development, progression, and
prognosis, yet a comprehensive classification system is lacking. To address this gap, we …

Dynamic roles of tumor-infiltrating B lymphocytes in cancer immunotherapy

S Song, C Wang, Y Chen, X Zhou, Y Han… - Cancer Immunology …, 2025 - Springer
The amazing diversity of B cells within the tumor microenvironment is the basis for the
diverse development of B cell-based immunotherapies. Here, we focus on elucidating the …

[HTML][HTML] PSMD2 表达对非小细胞肺癌预后及免疫微环境的影响

张姣, 訾瑞, 胡萍, 王燕 - Advances in Clinical Medicine, 2024 - hanspub.org
目的: 探索蛋白酶体26S 亚基非ATP 酶2 (Proteasome 26S Subunit, Non. ATPase2, PSMD2)
在非小细胞肺癌(Non-small cell lung cancer, NSCLC) 患者中的表达特征 …

Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding

J Gao, D Gu, K Yang, J Zhang, Q Lin, W Yuan, X Zhu… - Cancer cell, 2025 - cell.com
Glioblastoma is a highly aggressive primary brain tumor with glioblastoma stem cells (GSCs)
enforcing the intra-tumoral hierarchy. Plasma cells (PCs) are critical effectors of the B …