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Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape
A fundamental feature of cellular plasma membranes (PMs) is an asymmetric lipid
distribution between the bilayer leaflets. However, neither the detailed, comprehensive …
distribution between the bilayer leaflets. However, neither the detailed, comprehensive …
Insights into asymmetric liposomes as a potential intervention for drug delivery including pulmonary nanotherapeutics
YN Al Badri, CS Chaw, AA Elkordy - Pharmaceutics, 2023 - mdpi.com
Liposome-based drug delivery systems are nanosized spherical lipid bilayer carriers that
can encapsulate a broad range of small drug molecules (hydrophilic and hydrophobic …
can encapsulate a broad range of small drug molecules (hydrophilic and hydrophobic …
Seeing the membrane from both sides now: lipid asymmetry and its strange consequences
Almost all biomembranes are constructed as lipid bilayers and, in almost all of these, the two
opposing monolayers (leaflets) have distinct lipid compositions. This lipid asymmetry arises …
opposing monolayers (leaflets) have distinct lipid compositions. This lipid asymmetry arises …
On the mechanism of bilayer separation by extrusion, or why your LUVs are not really unilamellar
Extrusion through porous filters is a widely used method for preparing biomimetic model
membranes. Of primary importance in this approach is the efficient production of single …
membranes. Of primary importance in this approach is the efficient production of single …
Scaling relationships for the elastic moduli and viscosity of mixed lipid membranes
The elastic and viscous properties of biological membranes play a vital role in controlling
cell functions that require local reorganization of the membrane components as well as …
cell functions that require local reorganization of the membrane components as well as …
Building asymmetric lipid bilayers for molecular dynamics simulations: What methods exist and how to choose one?
The compositional asymmetry of biological membranes has attracted significant attention
over the last decade. Harboring more differences from symmetric membranes than …
over the last decade. Harboring more differences from symmetric membranes than …
Membrane structure–function insights from asymmetric lipid vesicles
E London - Accounts of chemical research, 2019 - ACS Publications
Conspectus The lipid bilayer, together with embedded proteins, is the central structure in
biomembranes. While artificial lipid bilayers are useful to model natural membranes, they …
biomembranes. While artificial lipid bilayers are useful to model natural membranes, they …
A mechanical mechanism for vitamin E acetate in e-cigarette/va**-associated lung injury
The outbreak of electronic-cigarette/va**-associated lung injury (EVALI) has made
thousands ill. This lung injury has been attributed to a physical interaction between toxicants …
thousands ill. This lung injury has been attributed to a physical interaction between toxicants …
[HTML][HTML] Model membrane systems used to study plasma membrane lipid asymmetry
It is well known that the lipid distribution in the bilayer leaflets of mammalian plasma
membranes (PMs) is not symmetric. Despite this, model membrane studies have largely …
membranes (PMs) is not symmetric. Despite this, model membrane studies have largely …
A guide to your desired lipid-asymmetric vesicles
M Krompers, H Heerklotz - Membranes, 2023 - mdpi.com
Liposomes are prevalent model systems for studies on biological membranes. Recently,
increasing attention has been paid to models also representing the lipid asymmetry of …
increasing attention has been paid to models also representing the lipid asymmetry of …