Antibiotic resistance genes from livestock waste: occurrence, dissemination, and treatment

Y He, Q Yuan, J Mathieu, L Stadler, N Senehi, R Sun… - NPJ Clean …, 2020 - nature.com
Antibiotics are widely used in animal husbandry, and various types of antibiotic resistance
genes (ARGs) are frequently detected in livestock waste around the world. Conventional …

Antimicrobial susceptibility testing for enterococci

A Khan, WR Miller, D Axell-House… - Journal of Clinical …, 2022 - journals.asm.org
Enterococci are major, recalcitrant nosocomial pathogens with a wide repertoire of intrinsic
and acquired resistance determinants and the potential of develo** resistance to all …

Phage-specific immunity impairs efficacy of bacteriophage targeting Vancomycin Resistant Enterococcus in a murine model

JD Berkson, CE Wate, GB Allen, AM Schubert… - Nature …, 2024 - nature.com
Bacteriophage therapy is a promising approach to address antimicrobial infections though
questions remain regarding the impact of the immune response on clinical effectiveness …

Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease

S Lindner, O Miltiadous, RJF Ramos, J Paredes… - Nature …, 2024 - nature.com
Microbial transformation of bile acids affects intestinal immune homoeostasis but its impact
on inflammatory pathologies remains largely unknown. Using a mouse model of graft-versus …

High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis

B Zhai, M Ola, T Rolling, NL Tosini, S Joshowitz… - Nature medicine, 2020 - nature.com
The intestinal microbiota is a complex community of bacteria, archaea, viruses, protists and
fungi,. Although the composition of bacterial constituents has been linked to immune …

[HTML][HTML] High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients

CL Nguyen, KA Markey, O Miltiadous, A Dai, N Waters… - Cell, 2023 - cell.com
Discerning the effect of pharmacological exposures on intestinal bacterial communities in
cancer patients is challenging. Here, we deconvoluted the relationship between drug …

Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease

M Burgos da Silva, DM Ponce, A Dai… - Blood, The Journal …, 2022 - ashpublications.org
Following allogeneic hematopoietic cell transplantation (allo-HCT), the gastrointestinal (GI)
tract is frequently affected by acute graft-versus-host disease (aGVHD), the pathophysiology …

Enhanced antibacterial properties on superhydrophobic micro‐nano structured titanium surface

VK Manivasagam, G Perumal… - Journal of Biomedical …, 2022 - Wiley Online Library
Micro/nano scale surface modifications of titanium based orthopedic and cardiovascular
implants has shown to augment biocompatibility. However, bacterial infection remains a …

Rare transmission of commensal and pathogenic bacteria in the gut microbiome of hospitalized adults

BA Siranosian, EF Brooks, T Andermann… - Nature …, 2022 - nature.com
Bacterial bloodstream infections are a major cause of morbidity and mortality among
patients undergoing hematopoietic cell transplantation (HCT). Although previous research …

Multidrug-resistant high-risk Enterococcus faecium clones: can we really define them?

AR Freitas, AP Pereira, C Novais, L Peixe - International journal of …, 2021 - Elsevier
Enterococcus faecium is a significant opportunistic human pathogen with a broad host
range, including humans, farm animals, pets and wildlife. Specialised subpopulations have …