Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 3 …

SH Kennedy, RW Lam, RS McIntyre… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Inflammation and the dimensions of depression: a review

M Majd, EFH Saunders, CG Engeland - Frontiers in neuroendocrinology, 2020 - Elsevier
Patients with depressive disorders show a wide range of clinical manifestations including
cognitive and neurovegetative symptoms. Importantly, these symptoms can differ in terms of …

The clinical characterization of the adult patient with depression aimed at personalization of management

M Maj, DJ Stein, G Parker, M Zimmerman… - World …, 2020 - Wiley Online Library
Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …

Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysis

V Nanni, R Uher, A Danese - American Journal of Psychiatry, 2012 - Am Psychiatric Assoc
Objectives: Evidence suggests that childhood maltreatment may negatively affect not only
the lifetime risk of depression but also clinically relevant measures of depression, such as …

Machine learning, statistical learning and the future of biological research in psychiatry

R Iniesta, D Stahl, P McGuffin - Psychological medicine, 2016 - cambridge.org
Psychiatric research has entered the age of 'Big Data'. Datasets now routinely involve
thousands of heterogeneous variables, including clinical, neuroimaging, genomic …

An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline

R Uher, KE Tansey, T Dew, W Maier… - American Journal of …, 2014 - Am Psychiatric Assoc
Objective: Major depressive disorder has been linked with inflammatory processes, but it is
unclear whether individual differences in levels of inflammatory biomarkers could help …

Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression

O Köhler-Forsberg, HN Buttenschøn, KE Tansey… - Brain, behavior, and …, 2017 - Elsevier
Introduction Population-based studies have associated inflammation, particularly higher C-
reactive protein (CRP), with depressive severity, but clinical trials in major depressive …

Reevaluating the efficacy and predictability of antidepressant treatments: a symptom clustering approach

AM Chekroud, R Gueorguieva, HM Krumholz… - JAMA …, 2017 - jamanetwork.com
Importance Depressive severity is typically measured according to total scores on
questionnaires that include a diverse range of symptoms despite convincing evidence that …

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2008 British Association for Psychopharmacology guidelines

A Cleare, CM Pariante, AH Young… - Journal of …, 2015 - journals.sagepub.com
A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms

R Uher, RH Perlis, N Henigsberg, A Zobel… - Psychological …, 2012 - cambridge.org
BackgroundSymptom dimensions have not yet been comprehensively tested as predictors
of the substantial heterogeneity in outcomes of antidepressant treatment in major depressive …