The multifaceted therapeutic role of N-acetylcysteine (NAC) in disorders characterized by oxidative stress

G Raghu, M Berk, PA Campochiaro… - Current …, 2021 - benthamdirect.com
Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous
cellular process implicated in the etiology of many illnesses. The sulfhydryl-containing …

Acute liver failure

W Bernal, J Wendon - New England Journal of Medicine, 2013 - Mass Medical Soc
Acute Liver Failure | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …

Acute liver failure guidelines

A Shingina, N Mukhtar, J Wakim-Fleming… - Official journal of the …, 2023 - journals.lww.com
Acute liver failure (ALF) is a rare, acute, potentially reversible condition resulting in severe
liver impairment and rapid clinical deterioration in patients without preexisting liver disease …

EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure

J Wendon, J Cordoba, A Dhawan, FS Larsen… - Journal of …, 2017 - Elsevier
The term acute liver failure (ALF) is frequently applied as a generic expression to describe
patients presenting with or develo** an acute episode of liver dysfunction. In the context of …

Oxidative stress in drug-induced liver injury (DILI): from mechanisms to biomarkers for use in clinical practice

M Villanueva-Paz, L Morán, N López-Alcántara… - Antioxidants, 2021 - mdpi.com
Idiosyncratic drug-induced liver injury (DILI) is a type of hepatic injury caused by an
uncommon drug adverse reaction that can develop to conditions spanning from …

Cell death and cell death responses in liver disease: mechanisms and clinical relevance

T Luedde, N Kaplowitz, RF Schwabe - Gastroenterology, 2014 - Elsevier
Hepatocellular death is present in almost all types of human liver disease and is used as a
sensitive parameter for the detection of acute and chronic liver disease of viral, toxic …

Acute liver failure

RT Stravitz, WM Lee - The Lancet, 2019 - thelancet.com
Acute liver failure is a rare and severe consequence of abrupt hepatocyte injury, and can
evolve over days or weeks to a lethal outcome. A variety of insults to liver cells result in a …

Interventions for paracetamol (acetaminophen) overdose

AL Chiew, C Gluud, J Brok… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Paracetamol (acetaminophen) is the most widely used non‐prescription
analgesic in the world. Paracetamol is commonly taken in overdose either deliberately or …

Acetaminophen-related hepatotoxicity

C Bunchorntavakul, KR Reddy - Clinics in liver disease, 2013 - liver.theclinics.com
Acetaminophen (APAP or paracetamol or N-acetyl-p-aminophenol), a safe and effective
antipyretic and analgesic, has been extensively used around the world since 1955. It is …

A review of acetaminophen poisoning

MJ Hodgman, AR Garrard - Critical care clinics, 2012 - criticalcare.theclinics.com
Acetaminophen (APAP) is a safe and effective analgesic and antipyretic. 1 It is widely
available as a single-component medication and also as a component of a plethora of …