Besides various infectious and inflammatory complications, recent studies also indicated the
significance of NLRP3 inflammasome in cancer progression and therapy. NLRP3-mediated …

Inflammation is a physiological mechanism of the immune response and has an important
role in maintaining the hematopoietic cell niche in the bone marrow. During this process, the …

Pyroptosis and macrophage pro-inflammatory activation play an important role in
hepatocellular carcinoma (HCC) progression. However, the specific regulatory mechanisms …

ABSTRACT Epithelial membrane protein 1 (EMP1) is a member of the small hydrophobic
membrane protein subfamily. EMP1 is aberrantly expressed in various tumor tissues and …

This study examines the prognostic role and immunological relevance of EMP1 (epithelial
membrane protein-1) in a pan-cancer analysis, with a focus on ovarian cancer. Utilizing data …

Objective To explore the mechanism of ursolic acid (UA) against acute B lymphoblastic
leukaemia (B-ALL) based on network pharmacological analysis, molecular docking and …

T‐cell acute lymphoblastic leukemia (T‐ALL) is a genetically heterogeneous disease,
characterized by an abnormal transformation of T cells into highly proliferative leukemic …

Reduced responsiveness of precursor B-acute lymphoblastic leukemia (BCP-ALL) to
chemotherapy can be inferred when leukemia cells persist after 28 days of initial treatment …

Background: Gene set analysis methods have played a major role in generating biological
interpretations from omics data such as gene expression datasets. However, most methods …

NLR family pyrin domain-containing 3 (NLRP3) is an intracellular protein that after
recognizing a broad spectrum of stressors, such as microbial motifs and endogenous …