[HTML][HTML] Innate lymphoid cells: 10 years on
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …
Cell fate specification and differentiation in the adult mammalian intestine
Intestinal stem cells at the bottom of crypts fuel the rapid renewal of the different cell types
that constitute a multitasking tissue. The intestinal epithelium facilitates selective uptake of …
that constitute a multitasking tissue. The intestinal epithelium facilitates selective uptake of …
A molecular single-cell lung atlas of lethal COVID-19
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2
infection,, but the host response at the lung tissue level is poorly understood. Here we …
infection,, but the host response at the lung tissue level is poorly understood. Here we …
[HTML][HTML] Organization of the human intestine at single-cell resolution
The intestine is a complex organ that promotes digestion, extracts nutrients, participates in
immune surveillance, maintains critical symbiotic relationships with microbiota and affects …
immune surveillance, maintains critical symbiotic relationships with microbiota and affects …
A single-cell survey of the small intestinal epithelium
Intestinal epithelial cells absorb nutrients, respond to microbes, function as a barrier and
help to coordinate immune responses. Here we report profiling of 53,193 individual …
help to coordinate immune responses. Here we report profiling of 53,193 individual …
Tales from the crypt: new insights into intestinal stem cells
The intestinal epithelium withstands continuous mechanical, chemical and biological insults
despite its single-layered, simple epithelial structure. The crypt–villus tissue architecture in …
despite its single-layered, simple epithelial structure. The crypt–villus tissue architecture in …
Homeostatic immunity and the microbiota
The microbiota plays a fundamental role in the induction, education, and function of the host
immune system. In return, the host immune system has evolved multiple means by which to …
immune system. In return, the host immune system has evolved multiple means by which to …
The intestinal epithelium: central coordinator of mucosal immunity
JM Allaire, SM Crowley, HT Law, SY Chang, HJ Ko… - Trends in …, 2018 - cell.com
The gastrointestinal (GI) tract represents a unique challenge to the mammalian immune
system. It must tolerate the presence of the luminal microbiota and thus not respond to their …
system. It must tolerate the presence of the luminal microbiota and thus not respond to their …
Nutritional components in Western diet versus Mediterranean diet at the gut microbiota–immune system interplay. Implications for health and disease
C García-Montero, O Fraile-Martínez… - Nutrients, 2021 - mdpi.com
The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …
The intestinal barrier and current techniques for the assessment of gut permeability
I Schoultz, ÅV Keita - Cells, 2020 - mdpi.com
The intestinal barrier is essential in human health and constitutes the interface between the
outside and the internal milieu of the body. A functional intestinal barrier allows absorption of …
outside and the internal milieu of the body. A functional intestinal barrier allows absorption of …