[HTML][HTML] Neuroinflammation and neurodegenerative diseases: how much do we still not know?

CR Balistreri, R Monastero - Brain sciences, 2023 - mdpi.com
The term “neuroinflammation” defines the typical inflammatory response of the brain closely
related to the onset of many neurodegenerative diseases (NDs). Neuroinflammation is well …

Glymphatic system pathology and neuroinflammation as two risk factors of neurodegeneration

S Szlufik, K Kopeć, S Szleszkowski, D Koziorowski - Cells, 2024 - mdpi.com
The key to the effective treatment of neurodegenerative disorders is a thorough
understanding of their pathomechanism. Neurodegeneration and neuroinflammation are …

Systemic and local immunosuppression in glioblastoma and its prognostic significance

AA Stepanenko, AO Sosnovtseva, MP Valikhov… - Frontiers in …, 2024 - frontiersin.org
The effectiveness of tumor therapy, especially immunotherapy and oncolytic virotherapy,
critically depends on the activity of the host immune cells. However, various local and …

Neurocysticercosis: The duration of its preclinical phase relies on the parasite location

CA Tellez‐Arellano, J Kuschick‐Fehér… - Tropical Medicine & …, 2024 - Wiley Online Library
Objectives Neurocysticercosis (NC) is a heterogeneous disease particularly in terms of
response to treatment and prognosis. Parasite localization is one of the main factors …

Dual role of vascular endothelial growth factor-C in post-stroke recovery

YH Choi, M Hsu, C Laaker, J Port, KG Kovács… - Journal of Experimental …, 2024 - rupress.org
Cerebrospinal fluid (CSF), antigens, and antigen-presenting cells drain from the central
nervous system (CNS) into lymphatic vessels near the cribriform plate and dura, yet the role …

Toward curing neurological autoimmune disorders: Biomarkers, immunological mechanisms, and therapeutic targets

Y Segal, J Soltys, BDS Clarkson, CL Howe, SR Irani… - Neuron, 2025 - cell.com
Autoimmune neurology is a rapidly expanding field driven by the discovery of neuroglial
autoantibodies and encompassing a myriad of conditions affecting every level of the …

Dual role of vascular endothelial growth factor-C (VEGF-C) in post-stroke recovery

YH Choi, M Hsu, C Laaker, M Herbath, H Yang… - bioRxiv, 2023 - biorxiv.org
Using a mouse model of ischemic stroke, this study characterizes stroke-induced
lymphangiogenesis at the cribriform plate (CP). While blocking CP lymphangiogenesis with …

Immune cell dynamics in irradiated gliomas

DA Agardy - 2025 - archiv.ub.uni-heidelberg.de
Surgical resection followed by adjuvant radio-chemotherapy remains the mainstay of glioma
management. However, the clinical benefit is highly limited. Therefore, there is an urgent …

The detection of serum anti-brain antibodies in a cohort of patients with tumefactive demyelinating lesions of the CNS.

MT Boyle - 2024 - ses.library.usyd.edu.au
Background: A tumefactive demyelinating lesion (TDL) is defined as being at least 2cm in
diameter, whilst conventional multiple sclerosis (CMS) lesions usually have a diameter less …