The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

SERS tags for biomedical detection and bioimaging

H Liu, X Gao, C Xu, D Liu - Theranostics, 2022 - pmc.ncbi.nlm.nih.gov
Surface-enhanced Raman scattering (SERS) has emerged as a valuable technique for
molecular identification. Due to the characteristics of high sensitivity, excellent signal …

Multiplexed imaging in oncology

C Andreou, R Weissleder, MF Kircher - Nature Biomedical Engineering, 2022 - nature.com
In oncology, technologies for clinical molecular imaging are used to diagnose patients,
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …

Ratiometric optical nanoprobes enable accurate molecular detection and imaging

X Huang, J Song, BC Yung, X Huang… - Chemical Society …, 2018 - pubs.rsc.org
Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

SERS-activated platforms for immunoassay: probes, encoding methods, and applications

Z Wang, S Zong, L Wu, D Zhu, Y Cui - Chemical reviews, 2017 - ACS Publications
Owing to their excellent multiplexing ability, high sensitivity, and large dynamic range,
immunoassays using surface-enhanced Raman scattering (SERS) as the readout signal …

Advances in nanotechnology for cancer biomarkers

F Ye, Y Zhao, R El-Sayed, M Muhammed, M Hassan - Nano Today, 2018 - Elsevier
Cancer biomarkers with high selectivity, specificity and reproducibility play essential role in
diagnosis, prognosis and prediction of treatment efficacy in cancer patients. However, the …

A Systematic Approach toward Enabling Maximal Targeting Efficiency of Cell Surface Proteins with Actively Targeted SERS Nanoparticles

P Bagheri, OE Eremina, A Fernando… - … Applied Materials & …, 2024 - ACS Publications
With their intricate design, nanoparticles (NPs) have become indispensable tools in the
quest for precise cellular targeting. Among various NPs, gold NPs stand out with unique …

Surface-enhanced Raman scattering nanoparticles for multiplexed imaging of bladder cancer tissue permeability and molecular phenotype

RM Davis, B Kiss, DR Trivedi, TJ Metzner, JC Liao… - Acs Nano, 2018 - ACS Publications
Bladder cancer has the highest recurrence rate of all cancers due in part to inadequate
transurethral resection. Inadequate resection is caused by the inability of cystoscopes to …

[HTML][HTML] Surface-enhanced Raman spectroscopy in cancer diagnosis, prognosis and monitoring

L Guerrini, RA Alvarez-Puebla - Cancers, 2019 - mdpi.com
As medicine continues to advance our understanding of and knowledge about the complex
and multifactorial nature of cancer, new major technological challenges have emerged in …

A clinically feasible diagnostic spectro-histology built on SERS-nanotags for multiplex detection and grading of breast cancer biomarkers

VP Murali, V Karunakaran, M Murali, A Lekshmi… - Biosensors and …, 2023 - Elsevier
Simultaneous detection of multiple biomarkers is always an obstacle in
immunohistochemical (IHC) analysis. Herein, a straightforward spectroscopy-driven …