Affective disorders, cognitive decline, and psychosis have long been recognized as common
in Parkinson disease (PD), and other psychiatric disorders include impulse control …

Mild cognitive impairment (PD-MCI) and dementia (PDD) are among the most frequent non-
motor symptoms in Parkinson's disease (PD). PD-MCI is six times more likely than age …

In the field of neurodegenerative diseases, especially sporadic Parkinson's disease (sPD)
with dementia (sPDD), the question of how the disease starts and spreads in the brain …

Background Brain structure abnormalities throughout the course of Parkinson's disease
have yet to be fully elucidated. Objective Using a multicenter approach and harmonized …

Mild cognitive impairment in Parkinson's disease is associated with progression to dementia
(Parkinson's disease dementia) in a majority of patients. Determining structural imaging …

We mapped the distribution of atrophy in Parkinson's disease (PD) using magnetic
resonance imaging (MRI) and clinical data from 232 PD patients and 117 controls from the …

Abstract See Gratwicke and Foltynie (doi: 10.1093/brain/awx333) for a scientific commentary
on this article. Cognitive impairments are a prevalent and disabling non-motor complication …

Here we test the hypothesis that the neurodegenerative process in Parkinson's disease (PD)
moves stereotypically along neural networks, possibly reflecting the spread of toxic alpha …

Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …

Mild cognitive changes, including executive dysfunction, are seen in Parkinson's Disease
(PD). Approximately 30% of individuals with PD develop Parkinson's disease dementia …