Alzheimer's disease (AD), a common neurodegenerative disease in the elderly and the most
prevalent cause of dementia, is characterized by progressive cognitive impairment. The …

The synapse has consistently been considered a vulnerable and critical target within
Alzheimer's disease, and synapse loss is, to date, one of the main biological correlates of …

Abstract Slow gamma oscillations (30–60 Hz) correlate with retrieval of spatial memory.
Altered slow gamma oscillations have been observed in Alzheimer's disease. Here, we use …

Gamma oscillations (∼ 25–100 Hz) are believed to play a role in cognition. Accordingly,
aberrant gamma oscillations have been observed in several cognitive disorders, including …

The presymptomatic phase of Alzheimer disease (AD) starts with the deposition of amyloid-β
in the cortex and begins a decade or more before the emergence of cognitive decline. The …

Alzheimer's disease (AD) is an irreversible and highly progressive neurodegenerative
disease. Clinically, patients with AD display impairments in episodic and spatial memory …

Alzheimer's disease (AD) is characterized by the classical hallmarks of Aβ-deposition and
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …

Whenever we navigate through different contexts, we build a cognitive map: an internal
representation of the territory. Spatial navigation is a complex skill that involves multiple …

The global recognition of the importance of physical exercise (PE) for human health has
resulted in increased research on its effects on cortical activity. Neural oscillations, which are …

Memory traces are reactivated selectively during sharp-wave ripples. The mechanisms of
selective reactivation, and how degraded reactivation affects memory, are poorly …