Standardizing workflows in imaging transcriptomics with the abagen toolbox

RD Markello, A Arnatkeviciute, JB Poline, BD Fulcher… - elife, 2021 - elifesciences.org
Gene expression fundamentally shapes the structural and functional architecture of the
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …

Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder

AM Buch, PE Vértes, J Seidlitz, SH Kim… - Nature …, 2023 - nature.com
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Structural, functional, and molecular imaging of autism spectrum disorder

X Li, K Zhang, X He, J Zhou, C **, L Shen, Y Gao… - Neuroscience …, 2021 - Springer
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder
associated with both genetic and environmental risks. Neuroimaging approaches have been …

Functional imaging studies of acute administration of classic psychedelics, ketamine, and MDMA: Methodological limitations and convergent results

S Linguiti, JW Vogel, VJ Sydnor, A Pines… - Neuroscience & …, 2023 - Elsevier
Functional magnetic resonance imaging (fMRI) is increasingly used to non-invasively study
the acute impact of psychedelics on the human brain. While fMRI is a promising tool for …

Atypical functional connectome hierarchy in autism

SJ Hong, R Vos de Wael, RAI Bethlehem… - Nature …, 2019 - nature.com
One paradox of autism is the co-occurrence of deficits in sensory and higher-order socio-
cognitive processing. Here, we examined whether these phenotypical patterns may relate to …

Patients with autism spectrum disorders display reproducible functional connectivity alterations

Š Holiga, JF Hipp, CH Chatham, P Garces… - Science Translational …, 2019 - science.org
Despite the high clinical burden, little is known about pathophysiology underlying autism
spectrum disorder (ASD). Recent resting-state functional magnetic resonance imaging (rs …

Population heterogeneity in clinical cohorts affects the predictive accuracy of brain imaging

O Benkarim, C Paquola, B Park, V Kebets, SJ Hong… - PLoS …, 2022 - journals.plos.org
Brain imaging research enjoys increasing adoption of supervised machine learning for
single-participant disease classification. Yet, the success of these algorithms likely depends …

Connectivity alterations in autism reflect functional idiosyncrasy

O Benkarim, C Paquola, B Park, SJ Hong… - Communications …, 2021 - nature.com
Autism spectrum disorder (ASD) is commonly understood as an alteration of brain networks,
yet case-control analyses against typically-develo** controls (TD) have yielded …

[HTML][HTML] Gabrb3 is required for the functional integration of pyramidal neuron subtypes in the somatosensory cortex

R Babij, C Ferrer, A Donatelle, S Wacks, AM Buch… - Neuron, 2023 - cell.com
Dysfunction of gamma-aminobutyric acid (GABA) ergic circuits is strongly associated with
neurodevelopmental disorders. However, it is unclear how genetic predispositions impact …

Frequency-specific brain network architecture in resting-state fMRI

S Kajimura, D Margulies, J Smallwood - Scientific Reports, 2023 - nature.com
The analysis of brain function in resting-state network (RSN) models, ascertained through
the functional connectivity pattern of resting-state functional magnetic resonance imaging (rs …