[HTML][HTML] Role of vitamin A in the immune system

Z Huang, Y Liu, G Qi, D Brand, SG Zheng - Journal of clinical medicine, 2018 - mdpi.com
Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and
development, and protecting epithelium and mucus integrity in the body. VitA is known as an …

An overview of the mechanism of action of the monoclonal antibody vedolizumab

T Wyant, E Fedyk, B Abhyankar - Journal of Crohn's and Colitis, 2016 - academic.oup.com
Vedolizumab is a novel therapeutic monoclonal antibody recently approved for the treatment
of moderately to severely active ulcerative colitis and Crohn's disease in adults who have …

A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model

A Kendirli, C de la Rosa, KF Lämmle, K Eglseer… - Nature …, 2023 - nature.com
Multiple sclerosis (MS) involves the infiltration of autoreactive T cells into the CNS, yet we
lack a comprehensive understanding of the signaling pathways that regulate this process …

Fat-soluble vitamins: updated review of their role and orchestration in human nutrition throughout life cycle with sex differences

RA Youness, A Dawoud, O ElTahtawy, MA Farag - Nutrition & Metabolism, 2022 - Springer
Age and Gender are vital determinants for the micronutrient demands of normal indviduals.
Among these micronutrients are vitamins that are required in small amounts for optimum …

The role of retinoic acid in tolerance and immunity

JA Hall, JR Grainger, SP Spencer, Y Belkaid - Immunity, 2011 - cell.com
Vitamin A elicits a broad array of immune responses through its metabolite, retinoic acid
(RA). Recent evidence indicates that loss of RA leads to impaired immunity, whereas excess …

Retinoic acid and retinoic acid receptors as pleiotropic modulators of the immune system

A Larange, H Cheroutre - Annual review of immunology, 2016 - annualreviews.org
Vitamin A is a multifunctional vitamin implicated in a wide range of biological processes. Its
control over the immune system and functions are perhaps the most pleiotropic not only for …

Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope map** and characterization

EW Newell, N Sigal, N Nair, BA Kidd… - Nature …, 2013 - nature.com
It is currently not possible to predict which epitopes will be recognized by T cells in different
individuals. This is a barrier to the thorough analysis and understanding of T-cell responses …

Retinoic acid as a modulator of T cell immunity

MR Bono, G Tejon, F Flores-Santibañez, D Fernandez… - Nutrients, 2016 - mdpi.com
Vitamin A, a generic designation for an array of organic molecules that includes retinal,
retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including …

[HTML][HTML] Novel drug delivery systems for inflammatory bowel disease

F Yasmin, H Najeeb, S Shaikh… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic illness characterized by relapsing
inflammation of the intestines. The disorder is stratified according to the severity and is …

Vedolizumab: potential mechanisms of action for reducing pathological inflammation in inflammatory bowel diseases

M Luzentales-Simpson, YCF Pang, A Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Inflammatory bowel diseases (IBD), encompassing ulcerative colitis (UC), and Crohn's
disease (CD), are a group of disorders characterized by chronic, relapsing, and remitting, or …