Miniaturization has improved significantly in the recent decade, which has enabled the
development of numerous microfluidic systems. Microfluidic technologies have shown great …

The use of engineered cells, tissues, and organs has the opportunity to change the way
injuries and diseases are treated. Commercialization of these groundbreaking technologies …

Efficient techniques for separating target cells from undiluted blood are necessary for
various diagnostic and research applications. This paper presents acoustic focusing in …

The in-flow focusing method, introduced herein, enables rapid and straightforward
measurements of the whole-channel acoustic energy of acoustic flow-through devices. The …

Circulating tumor cells (CTCs) play an important role in the prognosis and efficacy
evaluation of metastatic tumors. Since CTCs are present in very low concentrations in the …

Neuroblastoma is the most common extracranial solid tumor in children, accounting for 10%
to 20% of deaths of pediatric malignancies. Due to the poor prognosis and significant …

Existing marker-based methods of minimal residual disease (MRD) determination in
neuroblastoma do not effectively enrich for the circulating disease cell population. Given the …

An all-fiber integrated device capable of separating and counting particles is presented. A
sequence of silica fiber capillaries with various diameters and longitudinal cavities are used …

Background aims These last decades have seen the emergence and development of cell-
based therapies, notably those based on mesenchymal stromal cells (MSCs). The …

This chapter describes recent developments within microscale acoustofluidics where
applications targeting unmet needs in the life sciences and clinical medicine are in focus. A …