Human endogenous retrovirus-H long terminal repeat-associating 2 (HHLA2), a member of
the B7 family of co-signaling molecules, is aberrantly expressed in various human cancers …

Background Malignant clones of primary cutaneous T-cell lymphomas (CTCL) can show a
CD4+, CD8+ or T-cell receptor (TCR)-γδ+ phenotype, but their individual impact on tumour …

Chimeric antigen receptor (CAR)–T cell therapy shows impressive efficacy treating
hematologic malignancies but requires further optimization in solid tumors. Here, we …

Immunotherapy remains underexploited in acute myeloid leukemia (AML) compared to other
hematological malignancies. Currently, gemtuzumab ozogamicin is the only therapeutic …

Immunotherapy aimed at inhibiting the negative co-stimulatory molecule programmed cell
death-ligand 1 (PD-L1) has limited effectiveness, with clinical response rates remaining …

Cure rates for acute myeloid leukemia (AML) remain suboptimal; thus, new treatment
strategies are needed for this deadly disease. Artemisia campestris leaves hold significant …

Background Cervical cancer (CC) is a prevalent gynecological malignancy, contributing to a
substantial number of fatalities among women. MicroRNAs (miRNAs) have emerged as …

Melanoma is a lethal form of skin cancer that impacts one out of every five Americans and
ranks as the fifth most prevalent cancer among men and women in the United States …

not-yet-known not-yet-known not-yet-known unknown Cancer immunotherapy represents a
transformative strategy in modern oncology, utilizing the body's immune system to recognize …