The construction of the brain during embryonic development was thought to be largely
independent of its electrical activity. In this view, proliferation, migration and differentiation of …

At specific stages of development, nerve and muscle cells generate spontaneous electrical
activity that is required for normal maturation of intrinsic excitability and synaptic connectivity …

Individual neurons display characteristic firing patterns determined by the number and kind
of ion channels in their membranes. We describe experimental and computational studies …

Before the onset of hearing at postnatal day 12, mouse inner hair cells (IHCs) produce
spontaneous and evoked action potentials. These spikes are likely to induce …

Spontaneous [Ca2+] i transients were measured in the mouse neocortex from embryonic
day 16 (E16) to postnatal day 6 (P6). On the day of birth (P0), cortical neurones generated …

Voltage-and current-clamp recordings were made from acute slices of mouse cerebral
cortex from embryonic day 14 to postnatal day 17. We targeted cells in the migratory …

The body plan of the tadpole larva of ascidians, or sea-squirts, is widely presumed to be
close to that of the hypothetical ancestor of all chordate animal groups, including …

Dans son livre écrit en 1949, Hebb a proposé la corrélation de l'activation entre des
neurones pré-synaptiques et post-synaptiques en soulignant que le renforcement de la …

Ouabain‐induced inhibition of early heart development indicated that Na/K‐ATPase plays
an important role in maintaining normal ionic balances during differentiation of …

Waves of spontaneous electrical activity that are highly synchronized across large
populations of neurones occur throughout the develo** mammalian central nervous …