The complement cascade has long been recognized to play a key role in inflammatory and
degenerative diseases. It is a 'double edged'sword as it is necessary to maintain health, yet …

Spinal cord injury (SCI) results from various pathogenic factors that destroy the normal
structure and function of the spinal cord, subsequently causing sensory, motor, and …

Resting-state functional MRI (rs-fMRI) permits study of the brain's functional networks without
requiring participants to perform tasks. Robust changes in such resting state networks …

Objective To examine the effects of activity-based therapy (ABT) on neurologic function,
walking ability, functional independence, metabolic health, and community participation …

Objective To examine the effect of long-term lower extremity functional electrical stimulation
(FES) cycling on the physical integrity and functional recovery in people with chronic spinal …

Spinal cord injury (SCI) is a devastating condition characterized by disruption of axonal
connections, failure of axonal regeneration, and loss of motor and sensory function. The …

Membrane depolarization has been shown to play an important role in the neural
differentiation of stem cells and in the survival and function of mature neurons. Here, we …

Background Human central nervous system-stem cells grown as neurospheres (hCNS-
SCns) self-renew, are multipotent, and have potential therapeutic applications following …

Malfunctions at the site of neuromuscular junction (NMJ) of post-injuries or diseases are
major barriers to recovery of function. The ability to efficiently derive motor neurons (MN) …

An obstacle to early stem cell transplantation into the acutely injured spinal cord is poor
survival of transplanted cells. Transplantation of embryonic stem cells as substrate adherent …