Dynamic bioinks to advance bioprinting

FLC Morgan, L Moroni, MB Baker - Advanced healthcare …, 2020 - Wiley Online Library
The development of bioinks for bioprinting of cell‐laden constructs remains a challenge for
tissue engineering, despite vigorous investigation. Hydrogels to be used as bioinks must …

Advancing Synthetic Hydrogels through Nature‐Inspired Materials Chemistry

BG Soliman, AK Nguyen, JJ Gooding… - Advanced …, 2024 - Wiley Online Library
Synthetic extracellular matrix (ECM) mimics that can recapitulate the complex biochemical
and mechanical nature of native tissues are needed for advanced models of development …

The versatility of squaramides: From supramolecular chemistry to chemical biology

LA Marchetti, LK Kumawat, N Mao, JC Stephens… - Chem, 2019 - cell.com
This review covers recent advances in the use of the squaramide moiety in chemical
research. We focus on the varied applications of squaramides under the broad headings of …

Molecular Tuning of a Benzene‐1, 3, 5‐Tricarboxamide Supramolecular Fibrous Hydrogel Enables Control over Viscoelasticity and Creates Tunable ECM‐Mimetic …

S Hafeez, AA Aldana, H Duimel, FAA Ruiter… - Advanced …, 2023 - Wiley Online Library
Traditional synthetic covalent hydrogels lack the native tissue dynamics and hierarchical
fibrous structure found in the extracellular matrix (ECM). These dynamics and fibrous …

Hydrogels for large-scale expansion of stem cells

S Yin, Y Cao - Acta biomaterialia, 2021 - Elsevier
Stem cells demonstrate considerable promise for various preclinical and clinical
applications, including drug screening, disease treatments, and regenerative medicine …

Strategies to improve nanofibrous scaffolds for vascular tissue engineering

T Yao, MB Baker, L Moroni - Nanomaterials, 2020 - mdpi.com
The biofabrication of biomimetic scaffolds for tissue engineering applications is a field in
continuous expansion. Of particular interest, nanofibrous scaffolds can mimic the …

Supramolecular polymer bottlebrushes

FV Gruschwitz, T Klein, S Catrouillet… - Chemical …, 2020 - pubs.rsc.org
The field of supramolecular chemistry has long been known to generate complex materials
of different sizes and shapes via the self-assembly of single or multiple low molar mass …

Squaric acid analogues in medicinal chemistry

J Chasák, V Šlachtová, M Urban, L Brulíková - European Journal of …, 2021 - Elsevier
In this review, we summarize the published data on squaric acid analogues with a special
focus on their use in medicinal chemistry and as potential drugs. Squaric acid is an …

Anion-responsive self-assembled hydrogels of a phenylalanine–TREN conjugate allow sequential release of propranolol and doxorubicin

MK Pradhan, D Gupta, KR Namdev, C Miglani, A Pal… - Nanoscale, 2022 - pubs.rsc.org
Stimuli-responsive self-assembled and supramolecular hydrogels derived from peptide
amphiphiles have opened exciting new avenues in biomedicine and drug delivery. Herein …

Modular mixing of benzene-1, 3, 5-tricarboxamide supramolecular hydrogelators allows tunable biomimetic hydrogels for control of cell aggregation in 3D

S Hafeez, FR Passanha, AJ Feliciano, FAA Ruiter… - Biomaterials …, 2022 - pubs.rsc.org
Few synthetic hydrogels can mimic both the viscoelasticity and supramolecular fibrous
structure found in the naturally occurring extracellular matrix (ECM). Furthermore, the ability …