Almost all polymerase II transcripts undergo alternative pre-mRNA splicing. Here, we review
the functions of alternative splicing events that have been experimentally determined. The …

In the process of establishing more and more complete annotations of eukaryotic genomes,
a constantly growing number of alternative splicing (AS) events has been reported over the …

This paper reviews state-of-the-art knowledge on steroid biosynthesis pathways in the pig
and provides an updated characterization of the porcine genes involved in these pathways …

Molecular dynamics simulation is a widely employed computational technique for studying
the dynamic behavior of molecular systems over time. By simulating macromolecular …

Understanding the genomic underpinnings of thermal adaptation is a hot topic in eco-
evolutionary studies of parasites. Marine heteroxenous parasites have complex life cycles …

Abstract p63 belongs to a family of transcription factors, which, while demonstrating striking
conservation of functional domains, regulate distinct biological functions. Its principal role is …

Aberrant activation of NFκB orchestrates a critical role in tumor carcinogenesis; however, the
regulatory mechanisms underlying this activation are not fully understood. Here we report …

Machado–Joseph disease (MJD) is a late-onset neurodegenerative disorder that presents
clinical heterogeneity not completely explained by its causative mutation. MJD is caused by …

High-throughput DNA sequencing is increasing the amount of public complete genomes
even though a precise gene catalogue for each organism is not yet available. In this context …

We present a de novo transcriptome of the mosquito vector Culex pipiens, assembled by
sequences of susceptible and insecticide resistant larvae. The high quality of the assembly …