Polymeric excipients in the technology of floating drug delivery systems

EV Blynskaya, SV Tishkov, VP Vinogradov… - Pharmaceutics, 2022 - mdpi.com
The combination of targeted transport and improvement of the release profile of the active
pharmaceutical ingredient (API) is a current trend in the development of oral medicinal …

Polysaccharides based superabsorbent hydrogel from Linseed: Dynamic swelling, stimuli responsive on–off switching and drug release

MT Haseeb, MA Hussain, SH Yuk, S Bashir… - Carbohydrate …, 2016 - Elsevier
Swelling properties of Linseed hydrogel (LSH) were studied in deionized water and different
physiological pH values, ie, 1.2, 6.8 and 7.4. Analysis of the kinetics drawn from swelling …

Okra-Thioglycolic acid conjugate—Synthesis, characterization, and evaluation as a mucoadhesive polymer

NR Naveen, C Gopinath, M Kurakula - Processes, 2020 - mdpi.com
The success of mucoadhesive drug delivery systems relies on the type of polymer used,
which becomes adhesive naturally upon hydration. Intended polymers should be able to …

Clarithromycin and pantoprazole gastro-retentive floating bilayer tablet for the treatment of helicobacter pylori: formulation and characterization

G Ullah, A Nawaz, MS Latif, KU Shah, S Ahmad… - Gels, 2023 - mdpi.com
Bilayer/multilayer tablets have been introduced to formulate incompatible components for
compound preparations, but they are now more commonly used to tailor drug release. This …

[HTML][HTML] Linseed hydrogel based floating drug delivery system for fluoroquinolone antibiotics: Design, in vitro drug release and in vivo real-time floating detection

FA Sheikh, MA Hussain, MU Ashraf, MT Haseeb… - Saudi Pharmaceutical …, 2020 - Elsevier
Herein, we designed a novel gastroretentive drug delivery system as floating matrix tablets
based on a polysaccharide material from linseeds (Linum usitatissimum L.) for …

Gastro retentive drug delivery systems: A review

K Adibkia, S Ghanbarzadeh… - Journal of Reports in …, 2013 - journals.lww.com
Gastric emptying is a complex and extremely variable process. This causes the
unpredictability of the bioavailability of drug delivery systems. Gastro retentive drug delivery …

Chitosan cocrystals embedded alginate beads for enhancing the solubility and bioavailability of aceclofenac

M Ganesh, UJ Jeon, U Ubaidulla, P Hemalatha… - International journal of …, 2015 - Elsevier
Enhanced oral bioavailability of aceclofenac has been achieved using chitosan cocrystals of
aceclofenac and its entrapment into alginate matrix a super saturated drug delivery system …

[HTML][HTML] Design expert supported mathematical optimization of repaglinide gastroretentive floating tablets: In vitro and in vivo evaluation

NR Naveen, C Gopinath, DS Rao - Future Journal of Pharmaceutical …, 2017 - Elsevier
2. Materials and methods Repaglinide was kindly gifted by KP Labs, Hyderabad, India.
HPMC K 15M and xanthan gum were purchased from Loba Chemie Pvt Ltd; Mumbai …

A QbD approach for the fabrication of immediate and prolong buoyant cinnarizine tablet using polyacrylamide-g-corn fibre gum

S Sethi, B Mangla, S Kamboj, V Rana - International Journal of Biological …, 2018 - Elsevier
The main hurdle in the oral delivery of cinnarizine is its supersaturation, precipitation and re-
dissolution process, influencing the oral bioavailability. To overcome this problem, an …

Fabrication and in vitro/in vivo appraisal of metronidazole intra-gastric buoyant sustained-release tablets in healthy volunteers

MH Elkomy, HA Abou-Taleb, HM Eid, HA Yassin - Pharmaceutics, 2022 - mdpi.com
Helicobacter pylori is thought to be the most common cause of peptic and duodenal ulcers.
Eradication of this organism is now considered one of the lines of treatment of gastric and …