[HTML][HTML] Glucagon-like peptide 1 (GLP-1)

TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes

MHA Muskiet, L Tonneijck, MM Smits… - Nature Reviews …, 2017 - nature.com
The gastrointestinal tract—the largest endocrine network in human physiology—
orchestrates signals from the external environment to maintain neural and hormonal control …

Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's disease

E Blázquez, E Velázquez… - Frontiers in …, 2014 - frontiersin.org
Although the brain has been considered an insulin-insensitive organ, recent reports on the
location of insulin and its receptors in the brain have introduced new ways of considering …

Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease

DA Sandoval, DA D'Alessio - Physiological reviews, 2015 - journals.physiology.org
The preproglucagon gene (Gcg) is expressed by specific enteroendocrine cells (L-cells) of
the intestinal mucosa, pancreatic islet α-cells, and a discrete set of neurons within the …

[HTML][HTML] Adipose tissue in control of metabolism

L Luo, M Liu - Journal of endocrinology, 2016 - joe.bioscientifica.com
Adipose tissue plays a central role in regulating whole-body energy and glucose
homeostasis through its subtle functions at both organ and systemic levels. On one hand …

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

S Weggen, JL Eriksen, P Das, SA Sagi, R Wang… - Nature, 2001 - nature.com
Epidemiological studies have documented a reduced prevalence of Alzheimer's disease
among users of nonsteroidal anti-inflammatory drugs (NSAIDs),,,,. It has been proposed that …

The glucagon-like peptides

TJ Kieffer, J Francis Habener - Endocrine reviews, 1999 - academic.oup.com
Glucagon-Like Peptides | Endocrine Reviews | Oxford Academic Skip to Main Content
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An anorexic lipid mediator regulated by feeding

F Rodriguez de Fonseca, M Navarro, R Gomez… - Nature, 2001 - nature.com
Oleylethanolamide (OEA) is a natural analogue of the endogenous cannabinoid
anandamide. Like anandamide, OEA is produced in cells in a stimulus-dependent manner …

Food intake and eating behavior after bariatric surgery

W Al-Najim, NG Docherty… - Physiological …, 2018 - journals.physiology.org
Obesity is an escalating global chronic disease. Bariatric surgery is a very efficacious
treatment for obesity and its comorbidities. Alterations to gastrointestinal anatomy during …

Central control of body weight and appetite

SC Woods, DA D'Alessio - The Journal of Clinical Endocrinology …, 2008 - academic.oup.com
Context Energy balance is critical for survival and health, and control of food intake is an
integral part of this process. This report reviews hormonal signals that influence food intake …