Key determinants of success in fecal microbiota transplantation: From microbiome to clinic

S Porcari, N Benech, M Valles-Colomer, N Segata… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) has achieved satisfactory results in preventing the
recurrence of Clostridioides difficile infection, but these positive outcomes have only been …

Gut–liver axis: barriers and functional circuits

O Pabst, MW Hornef, FG Schaap, V Cerovic… - Nature Reviews …, 2023 - nature.com
The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …

The potential of Akkermansia muciniphila in inflammatory bowel disease

T Zhang, X Ji, G Lu, F Zhang - Applied microbiology and biotechnology, 2021 - Springer
Akkermansia muciniphila is a next-generation probiotic with significant application
prospects. The role of A. muciniphila in metabolic diseases and tumor immunotherapy has …

Advancing therapeutics for recurrent clostridioides difficile infections: an overview of vowst's FDA approval and implications

N Jain, TP Umar, AF Fahner, V Gibietis - Gut Microbes, 2023 - Taylor & Francis
Clostridioides difficile infections (CDI) are a leading cause of healthcare-associated
infections with a high relapse rate. Current treatment guidelines recommend fidaxomicin as …

Effect of probiotic supplementation on gut microbiota in patients with major depressive disorders: A systematic review

QX Ng, YL Lim, CYL Yaow, WK Ng, J Thumboo… - Nutrients, 2023 - mdpi.com
There is accumulating evidence on the beneficial effects of probiotic supplementation for
patients with depressive disorders. However, prior reviews on the topic have largely focused …

Holistic approach to immune checkpoint inhibitor-related adverse events

R Poto, T Troiani, G Criscuolo, G Marone… - Frontiers in …, 2022 - frontiersin.org
Immune checkpoint inhibitors (ICIs) block inhibitory molecules, such as cytotoxic T-
lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1), or its …

Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation

R Wu, R **ong, Y Li, J Chen, R Yan - Journal of Autoimmunity, 2023 - Elsevier
Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …

Encyclopedia of fecal microbiota transplantation: a review of effectiveness in the treatment of 85 diseases

Y Wang, S Zhang, TJ Borody, F Zhang - Chinese Medical Journal, 2022 - journals.lww.com
Fecal microbiota transplantation (FMT) has been used as a core therapy for treating
dysbiosis-related diseases by remodeling gut microbiota. The methodology and technology …

Safety of fecal microbiota, live-jslm (REBYOTA) in individuals with recurrent Clostridioides difficile infection: data from five prospective clinical trials

C Lee, T Louie, L Bancke… - Therapeutic …, 2023 - journals.sagepub.com
Background: Microbiota-based treatments reduce the incidence of recurrent Clostridioides
difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient …

Molecular mechanisms of microbiota-mediated pathology in irritable bowel syndrome

Y Mishima, S Ishihara - International journal of molecular sciences, 2020 - mdpi.com
Irritable bowel syndrome (IBS) is one of the most prevalent functional gastrointestinal
disorders, and accumulating evidence gained in both preclinical and clinical studies indicate …