Locomotor circuits in the mammalian spinal cord

O Kiehn - Annu. Rev. Neurosci., 2006 - annualreviews.org
Intrinsic spinal networks, known as central pattern generators (CPGs), control the timing and
pattern of the muscle activity underlying locomotion in mammals. This review discusses new …

The neural control of interlimb coordination during mammalian locomotion

A Frigon - Journal of neurophysiology, 2017 - journals.physiology.org
Neuronal networks within the spinal cord directly control rhythmic movements of the
arms/forelimbs and legs/hindlimbs during locomotion in mammals. For an effective …

Phenotypic characterization of speed-associated gait changes in mice reveals modular organization of locomotor networks

C Bellardita, O Kiehn - Current Biology, 2015 - cell.com
Studies of locomotion in mice suggest that circuits controlling the alternating between left
and right limbs may have a modular organization with distinct locomotor circuits being …

Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons

KJ Dougherty, L Zagoraiou, D Satoh, I Rozani… - Neuron, 2013 - cell.com
Locomotion is controlled by spinal networks that generate rhythm and coordinate left-right
and flexor-extensor patterning. Defined populations of spinal interneurons have been linked …

[HTML][HTML] The neural circuits and synaptic mechanisms underlying motor initiation in C. elegans

BJ Piggott, J Liu, Z Feng, SA Wescott, XZS Xu - Cell, 2011 - cell.com
C. elegans is widely used to dissect how neural circuits and genes generate behavior.
During locomotion, worms initiate backward movement to change locomotion direction …

Muscle proprioceptive feedback and spinal networks

U Windhorst - Brain research bulletin, 2007 - Elsevier
This review revolves primarily around segmental feedback systems established by muscle
spindle and Golgi tendon organ afferents, as well as spinal recurrent inhibition via Renshaw …

Role of EphA4 and EphrinB3 in local neuronal circuits that control walking

K Kullander, SJB Butt, JM Lebret, L Lundfald… - Science, 2003 - science.org
Local circuits in the spinal cord that generate locomotion are termed central pattern
generators (CPGs). These provide coordinated bilateral control over the normal limb …

Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers

M Ballermann, K Fouad - European Journal of Neuroscience, 2006 - Wiley Online Library
Although injured axons in mammalian spinal cords do not regenerate, some recovery of
locomotor function following incomplete injury can be observed in patients and animal …

Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences

I Steuer, PA Guertin - Reviews in the Neurosciences, 2019 - degruyter.com
Central pattern generators (CPGs) are generally defined as networks of neurons capable of
enabling the production of central commands, specifically controlling stereotyped, rhythmic …

Physiological, anatomical and genetic identification of CPG neurons in the develo** mammalian spinal cord

O Kiehn, SJB Butt - Progress in neurobiology, 2003 - Elsevier
The basic motor patterns underlying rhythmic limb movements during locomotion are
generated by neuronal networks located within the spinal cord. These networks are called …