Alzheimer's disease (AD) is the most common form of dementia affecting the elderly
population today; however, there is currently no accurate description of the etiology of this …

The biomedical literature on the subject of neurotrophic growth factors has expanded
prodigiously. This essay reviews neurotrophic factors (NTF) and their receptors in …

The aversive aspects of withdrawal from chronic nicotine exposure are thought to be an
important motivational factor contributing to the maintenance of the tobacco habit in human …

Activation of neuronal nicotinic acetylcholine receptors (nAChRs) has been shown to
maintain cognitive function following aging or the development of dementia. Nicotine and …

Introduction 3. Epidemiological studies of smoking and Alzheimer's or Parkinson's disease
4. Expression and function of nicotinic acetylcholine receptors in Parkinson's disease …

Objective: To test the hypothesis that cigarette smoking protects against the development of
PD. Background: Smoking has been inversely associated with PD in many studies, but …

We have examined neuroanatomical, biochemical and endocrine parameters and spatial
learning in mice lacking the β2 subunit of the nicotinic acetylcholine receptor (nAChR) …

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
1 to 3% of individuals over the age of 65 years. While effective therapy exists for treating the …

There exists a remarkable diversity of neurotransmitter compounds in the striatum, a pivotal
brain region in the pathology of Parkinson's disease, a movement disorder characterized by …

Nearly all smokers begin tobacco use in adolescence, and approximately 25% of US
teenagers are daily smokers. Prenatal nicotine exposure is known to produce brain damage …