Gambling disorder is characterized by a persistent, recurrent pattern of gambling that is
associated with substantial distress or impairment. The prevalence of gambling disorder has …

Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …

Motivational and motor deficits are common in patients with depression and other psychiatric
disorders, and are related to symptoms of anhedonia and motor retardation. These deficits in …

One fundamental question concerning brain reward mechanisms is to determine how
reward-related activity is influenced by the nature of rewards. Here, we review the …

Background: Several behaviors, besides psychoactive substance ingestion, produce short-
term reward that may engender persistent behavior, despite knowledge of adverse …

There is evidence that the neural mechanisms underlying Internet Gaming Disorder (IGD)
resemble those of drug addiction. Functional Magnetic Resonance Imaging (fMRI) studies of …

To better understand the reward circuitry in human brain, we conducted activation likelihood
estimation (ALE) and parametric voxel-based meta-analyses (PVM) on 142 neuroimaging …

The clinical diagnosis of Parkinson's disease rests on the identification of the characteristics
related to dopamine deficiency that are a consequence of degeneration of the substantia …