Autism spectrum disorder (ASD) has become a common neurodevelopmental disorder. The
heterogeneity of ASD poses great challenges for its research and clinical translation. On the …

DNA methylation, one of the most well-studied epigenetic modifications, is involved in a
wide spectrum of biological processes. Epigenetic mechanisms control cellular morphology …

Rett syndrome (RTT) is defined as a rare disease caused by mutations of the methyl-CpG
binding protein 2 (MECP2). It is one of the most common causes of genetic mental …

Rett Syndrome (RTT) is a progressive X-linked neurodevelopmental disorder with no cure.
RTT patients show disease-associated symptoms within 18 months of age that include …

Simple Summary Rett syndrome (RTT) is a genetic disorder caused by mutations in the X-
chromosome. These mutations distort the function of a protein (methyl-CpG-binding protein …

Rett syndrome (RTT, online MIM 312750) is a devastating neurodevelopmental disorder
characterized by motor and cognitive disabilities. It is mainly caused by pathogenetic …

Genes mutated in monogenic neurodevelopmental disorders are broadly expressed. This
observation supports the concept that monogenic neurodevelopmental disorders are …

Rett syndrome is an X‐linked neurodevelopmental disorder caused by mutation of Mecp2
gene and primarily affects females. Glial cell dysfunction has been implicated in in Rett …

Rett syndrome (RTT) is a severe neurodevelopmental disorder that typically arises from
spontaneous germline mutations in the X-chromosomal methyl-CpG binding protein 2 …

Loss-of-function mutations in MECP2 are associated to Rett syndrome (RTT), a severe
neurodevelopmental disease. Mainly working as a transcriptional regulator, MeCP2 …