Objective To investigate the effects of intraoperative methadone in comparison with those of
standard-of-care intraoperative opioids, such as fentanyl and morphine, on pain scores …

Abstract Background Duloxetine is a Food and Drug Administration–approved selective
norepinephrine reuptake inhibitor for treating depression, anxiety, fibromyalgia, and …

Background: Pain is one of the major concerns of patients underwent Total Knee
Arthroplasty (TKA); appropriate pain management is a key factor in patient's early physical …

Postsurgical pain is normally perceived as nociceptive pain. Surgical trauma has been
known to induce central and peripheral sensitization and hyperalgesia, which in untreated …

Background: Postoperative pain is a common complication that can lead to serious
morbidities and delayed recovery. Objectives: The aim of this study was to investigate the …

Background Although opioids are the main choice for acute postoperative pain control,
many side effects have been reported for them. NSAIDs and paracetamol have been used …

Purpose Postoperative pain management has always been a significant challenge for both
hospital staff and surgical patients. Determination of pain management outcomes among …

Background Tonsillectomy with or without adenoidectomy is one of the most common
surgical procedures performed worldwide, especially for children. Oral honey administration …

A novel bioresorbable drug-eluting polycaprolactone (PCL) mesh scaffold was developed,
utilizing a solvent-cast additive manufacturing technique, to promote therapy of muscle …

Background Postoperative tissue adhesion is a major concern for most surgeons and is a
nearly unpreventable complication after abdominal or pelvic surgeries. This study explored …