Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a
branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial …

Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound
is silybin, which has a remarkable biological effect. It is used in different liver disorders …

Silymarin (SM), an extract from the Silybum marianum (milk thistle) plant containing various
flavonolignans (with silybin being the major one), has received a tremendous amount of …

Cardiac ATP production primarily depends on oxidative phosphorylation in mitochondria
and is dynamically regulated by Ca 2+ levels in the mitochondrial matrix as well as by …

Metabolic syndrome describes a complex metabolic risk factors including obesity,
hypertension, dyslipidemia, and diabetes. This syndrome is diagnosed by medical …

The only currently recommended treatment for nonalcoholic fatty liver disease (NAFLD) is
lifestyle modification. Preliminary studies of silybin showed beneficial effects on liver …

Silibinin, or silybin, is a polyphenolic flavonoid and the main active component of silymarin,
isolated from the seeds of the milk thistle plant (Silybum marianum). It has been shown to …

Nowadays, the nonalcoholic fatty liver disease represents the main chronic liver disease in
the Western countries, and the correct medical therapy remains a big question for the …

Diabetes mellitus (DM) is a metabolic disorder disease, and the number of diabetic patients
will reach 578 million by 2030 predictably. Currently, 8 classes of small molecular drugs are …

This study was carried out to evaluate whether silymarin supplementation influences growth,
lipid metabolism, and health status in grass carp fed elevated dietary lipid levels. The …