Recent applications of ATR FTIR spectroscopy and imaging to proteins

SE Glassford, B Byrne, SG Kazarian - Biochimica et Biophysica Acta (BBA) …, 2013 - Elsevier
Abstract Attenuated Total Reflection (ATR) Fourier Transform Infrared (FTIR) spectroscopy is
a label-free, non-destructive analytical technique that can be used extensively to study a …

Pharmaceutical applications of vibrational chemical imaging and chemometrics: a review

C Gendrin, Y Roggo, C Collet - Journal of pharmaceutical and biomedical …, 2008 - Elsevier
The emergence of chemical imaging (CI) has gifted spectroscopy an additional dimension.
Chemical imaging systems complement chemical identification by acquiring spatially …

Practical issues of hyperspectral imaging analysis of solid dosage forms

JM Amigo - Analytical and bioanalytical chemistry, 2010 - Springer
Hyperspectral imaging techniques have widely demonstrated their usefulness in different
areas of interest in pharmaceutical research during the last decade. In particular, middle …

[BOOK][B] Raman, infrared, and near-infrared chemical imaging

S Sasic, Y Ozaki - 2011 - books.google.com
An all-inclusive guide on the analytical methods of Raman, infrared, and near-infrared
chemical imaging An underutilized technology, chemical imaging through Raman, infrared …

Application of Fourier transform infrared spectrophotometry in pharmaceutical drugs analysis

AA Bunaciu, HY Aboul-Enein… - Applied Spectroscopy …, 2010 - Taylor & Francis
This review provides some background to infrared spectroscopy including Fourier transform
infrared spectroscopy. It is not meant to be complete or exhaustive but to provide the reader …

Application of mid-IR spectroscopy for the characterization of pharmaceutical systems

B Van Eerdenbrugh, LS Taylor - International journal of pharmaceutics, 2011 - Elsevier
In this article, the use of mid-IR in pharmaceutical settings is reviewed. An overview of mid-
IR instrumentation and sampling techniques is provided. Subsequently, different …

High-throughput thermal stability analysis of a monoclonal antibody by attenuated total reflection FT-IR spectroscopic imaging

M Boulet-Audet, B Byrne, SG Kazarian - Analytical chemistry, 2014 - ACS Publications
The use of biotherapeutics, such as monoclonal antibodies, has markedly increased in
recent years. It is thus essential that biotherapeutic production pipelines are as efficient as …

Impact of polymers on the crystallization and phase transition kinetics of amorphous nifedipine during dissolution in aqueous media

SA Raina, DE Alonzo, GGZ Zhang, Y Gao… - Molecular …, 2014 - ACS Publications
The commercial and clinical success of amorphous solid dispersions (ASD) in overcoming
the low bioavailability of poorly soluble molecules has generated momentum among …

Applications of Fourier transform infrared spectroscopic imaging to tablet dissolution and drug release

SG Kazarian, AV Ewing - Expert Opinion on Drug Delivery, 2013 - Taylor & Francis
Introduction: Solid oral dosage forms are the most commonly used method for administering
active pharmaceutical ingredients to patients. Understanding the mechanisms and …

Attenuated total reflection-Fourier transform infrared spectroscopic imaging of pharmaceuticals in microfluidic devices

AV Ewing, GS Clarke, SG Kazarian - Biomicrofluidics, 2016 - pubs.aip.org
The poor aqueous solubility of many active pharmaceutical ingredients presents challenges
for effective drug delivery. In this study, the combination of attenuated total reflection (ATR) …